IL1RAPL1 抗体 (C-Term)
Our Local Distributor
北京 101111
Quick Overview for IL1RAPL1 抗体 (C-Term) (ABIN8103314)
抗原
See all IL1RAPL1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
原理
- IL1RAPL1 Antibody - C-terminal region
-
序列
- YEYDVPPTGT LPLTSIGNQH TYCNIPMTLI NGQRPQTKSS REQNPDEAHT
-
纯化方法
- Affinity purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human IRPL1
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
说明
-
We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP73886-100UG
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.5 mg/mL
-
缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- prevent freeze-thaw cycles
-
储存条件
- 4 °C,-20 °C
-
储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
-
- IL1RAPL1 (Interleukin 1 Receptor Accessory Protein-Like 1 (IL1RAPL1))
-
别名
- IL1RAPL1
-
背景
-
Background Information: The protein encoded by this gene is a member of the interleukin 1 receptor family and is similar to the interleukin 1 accessory proteins. This protein has an N-terminal signal peptide, three extracellular immunoglobulin Ig-like domains, a transmembrane domain, an intracellular Toll/IL-1R domain, and a long C-terminal tail which interacts with multiple signalling molecules. This gene is located at a region on chromosome X that is associated with a non-syndromic form of X-linked intellectual disability. Deletions and mutations in this gene were found in patients with intellectual disability. This gene is expressed at a high level in post-natal brain structures involved in the hippocampal memory system, which suggests a specialized role in the physiological processes underlying memory and learning abilities, and plays a role in synapse formation and stabilization.
Gene Name: interleukin 1 receptor accessory protein like 1
Alternative Symbols: IL1R8, MRX10, MRX21, MRX34, OPHN4, IL1RAPL, TIGIRR-2, IL1RAPL-1, IL-1RAPL-1, IL-1-RAPL-1
Protein Name: interleukin-1 receptor accessory protein-like 1
-
分子量
- 76kDa
-
基因ID
- 11141
-
NCBI登录号
- XP_005274498
-
UniProt
- Q9NZN1
-
途径
- Synaptic Membrane, Growth Factor Binding
抗原
-