GLDC 抗体
Our Local Distributor
北京 101111
Quick Overview for GLDC 抗体 (ABIN8101741)
抗原
See all GLDC 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- GLDC Antibody
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序列
- LENSGWITQY TPYQPEVSQG RLESLLNYQT MVCDITGLDM ANASLLDEGT
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 100%
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the following sequence LENSGWITQYTPYQPEVSQGRLESLLNYQTMVCDITGLDMANASLLDEGT
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54297-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- GLDC (Glycine Dehydrogenase (GLDC))
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别名
- GLDC
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背景
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Background Information: Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the P protein, which binds to glycine and enables the methylamine group from glycine to be transferred to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH).
Gene Name: glycine dehydrogenase (decarboxylating)
Alternative Symbols: GCE, GCSP, HYGN1
Protein Name: Glycine dehydrogenase [decarboxylating], mitochondrial
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分子量
- 113 kDa
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基因ID
- 2731
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NCBI登录号
- NP_000161
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UniProt
- P23378
抗原
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