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GCSH 抗体

The 兔 多克隆 anti-GCSH antibody is suitable to detect GCSH in samples from 人, 小鼠, 大鼠, Cow, 犬, 马, 兔 和 豚鼠. It has been validated for IHC.
产品编号 ABIN8101739
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for GCSH 抗体 (ABIN8101739)

抗原

See all GCSH 抗体
GCSH (Glycine Cleavage System H Protein (GCSH))

适用

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人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠

宿主

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兔

克隆类型

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多克隆

标记

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This GCSH antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)
  • 原理

    GCSH Antibody

    序列

    IGTVGISNFA QEALGDVVYC SLPEVGTKLN KQDEFGALES VKAASELYSP

    预测反应

    Cow: 93%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 100%

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the following sequence IGTVGISNFAQEALGDVVYCSLPEVGTKLNKQDEFGALESVKAASELYSP
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64204-100UG

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    prevent freeze-thaw cycles

    储存条件

    4 °C,-20 °C

    储存方法

    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    GCSH (Glycine Cleavage System H Protein (GCSH))

    别名

    GCSH

    背景

    Background Information: Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the H protein, which transfers the methylamine group of glycine from the P protein to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH). Two transcript variants, one protein-coding and the other probably not protein-coding,have been found for this gene. Also, several transcribed and non-transcribed pseudogenes of this gene exist throughout the genome.

    Gene Name: glycine cleavage system protein H (aminomethyl carrier)

    Alternative Symbols: GCE, NKH

    Protein Name: Glycine cleavage system H protein, mitochondrial

    分子量

    19 kDa

    基因ID

    2653

    NCBI登录号

    NP_004474

    UniProt

    P23434
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