CDKN2C 抗体
Our Local Distributor
北京 101111
Quick Overview for CDKN2C 抗体 (ABIN8098208)
抗原
See all CDKN2C 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- CDKN2C Antibody
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序列
- VMKLGNPEIA RRLLLRGANP DLKDRTGFAV IHDAARAGFL DTLQTLLEFQ
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 91%, Pig: 100%, Rabbit: 100%, Rat: 92%
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the following sequence VMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQ
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP30196-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- CDKN2C (Cyclin-Dependent Kinase Inhibitor 2C (p18, Inhibits CDK4) (CDKN2C))
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别名
- CDKN2C
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背景
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Background Information: The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode an identical protein, have been reported.
Gene Name: cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
Alternative Symbols: p18, INK4C, p18-INK4C
Protein Name: Cyclin-dependent kinase 4 inhibitor C
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分子量
- 18 kDa
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基因ID
- 1031
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NCBI登录号
- NP_001253
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UniProt
- P42773
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途径
- Cell Division Cycle, Mitotic G1-G1/S Phases
抗原
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