ADAM15 抗体 (AA 621-720)
Quick Overview for ADAM15 抗体 (AA 621-720) (ABIN758771)
抗原
See all ADAM15 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 621-720
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交叉反应
- 人
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human ADAM15
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亚型
- IgG
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- ADAM15 (ADAM Metallopeptidase Domain 15 (ADAM15))
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别名
- ADAM15
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背景
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Synonyms: A disintegrin and metalloproteinase domain 15, ADA15_HUMAN, ADAM 15, ADAM metallopeptidase domain 15, Adam15, and cysteine-rich protein 15, Disintegrin and metalloproteinase domain-containing protein 15, disintegrin-like, EC 3.4.24., MDC 15, MDC-15, MDC15, Metalloprotease RGD disintegrin protein, Metalloproteinase like disintegrin like and cysteine rich protein 15, Metalloproteinase-like, Metargidin.
Background: ADAM15 is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.
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基因ID
- 8751
抗原
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