PGAM2 抗体 (N-Term)
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Quick Overview for PGAM2 抗体 (N-Term) (ABIN8093409)
抗原
See all PGAM2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- PGAM2 Antibody / Phosphoglycerate mutase 2
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纯化方法
- Immunogen affinity purified
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human Phosphoglycerate mutase 2 was used as the immunogen for the PGAM2 antibody.
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亚型
- IgG
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anti-phosphoglycerate Mutase 2 (Muscle) (PGAM2) antibody
PGAM2 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-phosphoglycerate Mutase 2 (Muscle) (PGAM2) antibodyPGAM2 适用: 人, 小鼠, 大鼠, 犬, 猴 WB, IF 宿主: 小鼠 Monoclonal 2F5 unconjugated
anti-phosphoglycerate Mutase 2 (Muscle) (PGAM2) (AA 1-236) antibodyPGAM2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-phosphoglycerate Mutase 2 (Muscle) (PGAM2) (AA 12-41), (N-Term) antibodyPGAM2 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB25799 unconjugated
anti-phosphoglycerate Mutase 2 (Muscle) (PGAM2) (AA 1-253) antibodyPGAM2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-phosphoglycerate Mutase 2 (Muscle) (PGAM2) (AA 1-253) antibodyPGAM2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-phosphoglycerate Mutase 2 (Muscle) (PGAM2) (Internal Region) antibodyPGAM2 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-phosphoglycerate Mutase 2 (Muscle) (PGAM2) (AA 1-253) antibodyPGAM2 适用: 人 WB, IF, ELISA, ICC 宿主: 小鼠 Monoclonal AT5A7 unconjugated
anti-phosphoglycerate Mutase 2 (Muscle) (PGAM2) antibodyPGAM2 适用: 人, 小鼠, 猴 WB, IHC, IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal 4E9 unconjugated
anti-phosphoglycerate Mutase 2 (Muscle) (PGAM2) antibodyPGAM2 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the PGAM2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the PGAM2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- PGAM2 (phosphoglycerate Mutase 2 (Muscle) (PGAM2))
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别名
- PGAM2
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背景
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PGAM2 antibody targets Phosphoglycerate mutase 2, encoded by the PGAM2 gene. Phosphoglycerate mutase 2 is a cytoplasmic enzyme that catalyzes the reversible interconversion of 3-phosphoglycerate and 2-phosphoglycerate during glycolysis. As a muscle-enriched isoform of phosphoglycerate mutase, PGAM2 plays a critical role in regulating glycolytic flux in tissues with high energetic demand.
Functionally, Phosphoglycerate mutase 2 contributes to efficient ATP production by facilitating a key step in the central glycolytic pathway. Its activity supports rapid energy generation required for muscle contraction and other energy-intensive cellular processes. A PGAM2 antibody supports studies focused on carbohydrate metabolism, glycolytic regulation, and metabolic adaptation in differentiated tissues.
PGAM2 is predominantly localized to the cytoplasm, consistent with its role in glycolysis. Although highly enriched in skeletal and cardiac muscle, PGAM2 expression can also be detected in other cell types under conditions that demand increased glycolytic activity. This distribution reflects a balance between tissue specialization and broader metabolic responsiveness.
From a disease-related perspective, altered PGAM2 expression or activity has been investigated in muscle disorders, metabolic disease, and cancer. Changes in glycolytic enzyme expression can influence cellular energy balance, proliferation, and stress tolerance. As such, Phosphoglycerate mutase 2 is frequently studied in contexts linking metabolism to disease-associated phenotypes.
At the molecular level, Phosphoglycerate mutase 2 functions as a dimeric enzyme and contains conserved catalytic residues required for phosphotransfer activity. Its apparent behavior in biochemical assays may vary depending on metabolic state and post-translational regulation without altering its primary structure. PGAM2 antibody reagents enable investigation of glycolytic enzyme regulation and cellular metabolism, with NSJ Bioreagents providing reagents intended for research use. -
UniProt
- P15259
抗原
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