IL3RA 抗体 (AA 26-171)
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北京 101111
Quick Overview for IL3RA 抗体 (AA 26-171) (ABIN8093269)
抗原
See all IL3RA 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 26-171
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原理
- IL3RA Antibody / Interleukin-3 receptor subunit alpha
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免疫原
- A recombinant fragment of human IL3RA protein (around amino acids 26-171) (exact sequence is proprietary) was used as the immunogen for the Interleukin-3 receptor alpha chain antibody.
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亚型
- IgG2b, kappa
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anti-Interleukin 3 Receptor, alpha (IL3RA) (AA 200-305) antibody
IL3RA 适用: 人 FACS, IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 8E11C5 unconjugated
anti-Interleukin 3 Receptor, alpha (IL3RA) antibody (PE)IL3RA 适用: 人 FACS 宿主: 小鼠 Monoclonal 6H6 PE
anti-Interleukin 3 Receptor, alpha (IL3RA) (AA 19-158) antibodyIL3RA 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 3 Receptor, alpha (IL3RA) (AA 201-300) antibodyIL3RA 适用: 人 FACS, WB, IHC (p), IHC (fro), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 3 Receptor, alpha (IL3RA) antibodyIL3RA 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 3 Receptor, alpha (IL3RA) (AA 26-171) antibodyIL3RA 适用: 人 IHC, ELISA 宿主: 兔 Monoclonal IL3RA-2947R unconjugated Recombinant Antibody
anti-Interleukin 3 Receptor, alpha (IL3RA) (AA 1-100) antibodyIL3RA 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 3 Receptor, alpha (IL3RA) antibodyIL3RA 适用: 人 FACS, WB, IP, IHC (fro) 宿主: 小鼠 Monoclonal 6H6 unconjugated
anti-Interleukin 3 Receptor, alpha (IL3RA) antibody (PerCP)IL3RA 适用: 人 FACS 宿主: 小鼠 Monoclonal 6H6 PerCP
anti-Interleukin 3 Receptor, alpha (IL3RA) antibody (Biotin)IL3RA 适用: 人 FACS, WB, IP, IHC (fro) 宿主: 小鼠 Monoclonal 6H6 Biotin
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应用备注
- Optimal dilution of the Interleukin-3 receptor alpha chain antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.05 % BSA, 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Interleukin-3 receptor alpha chain antibody with sodium azide - store at 2 to 8oC, antibody without sodium azide - store at -20 to -80oC.
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- IL3RA (Interleukin 3 Receptor, alpha (IL3RA))
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别名
- IL3RA
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背景
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Interleukin-3 receptor alpha chain antibody targets Interleukin 3 receptor alpha, a type I transmembrane cytokine receptor subunit that serves as the ligand-binding component of the interleukin-3 receptor complex. Interleukin-3 receptor alpha chain is primarily localized to the cell surface and associates with the shared beta chain to enable intracellular signaling following cytokine engagement. This receptor system plays an important role in regulating hematopoietic cell survival, proliferation, and differentiation during immune development and homeostasis.
Interleukin 3 receptor alpha chain expression is dynamically regulated across hematopoietic lineages and developmental stages. The receptor is expressed on hematopoietic stem and progenitor cells, monocytes, basophils, plasmacytoid dendritic cells, and select immune cell populations, reflecting its involvement in early immune cell specification and functional maturation. Because of this expression pattern, antibody-based detection of Interleukin 3 receptor alpha chain is widely used in research examining cytokine responsiveness, lineage commitment, and immune cell differentiation within the hematopoietic system.
Signaling through Interleukin 3 receptor alpha influences multiple intracellular pathways associated with cell survival and proliferative capacity following cytokine stimulation. These signaling events contribute to immune cell expansion and maintenance under both physiological and disease-associated conditions. Altered expression of Interleukin 3 receptor alpha chain has been reported in hematologic disorders, including myeloid neoplasms, where increased receptor expression is frequently observed on malignant cell populations. As a result, Interleukin-3 receptor alpha chain antibody reagents are commonly applied in studies investigating dysregulated cytokine signaling and immune cell abnormalities in disease models.
Beyond disease-focused research, Interleukin 3 receptor alpha chain remains relevant to broader investigations of immune activation, inflammatory signaling, and cytokine-driven cellular responses. Because receptor expression reflects cytokine sensitivity rather than antigen specificity, antibody-based detection provides insight into immune signaling potential across diverse experimental contexts. Clone IL3RA/1822 is designed to recognize Interleukin 3 receptor alpha chain and supports research applications focused on immune regulation, hematopoiesis, and cytokine receptor biology. NSJ Bioreagents offers this antibody for research use. -
UniProt
- P26951
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途径
- JAK/STAT Signaling
抗原
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