Recombinant HSPH1 抗体 (C-Term)
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北京 101111
Quick Overview for Recombinant HSPH1 抗体 (C-Term) (ABIN8093227)
抗原
See all HSPH1 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- C-Term
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原理
- HSPH1 Antibody / Heat shock protein 105 kDa (azide and preservative free)
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免疫原
- Prokaryotic recombinant protein of 31 kD corresponding to the C-terminus of the heat shock protein 105 molecule was used as the immunogen for the HSPH1/Heat shock protein 105 kDa antibody.
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亚型
- IgG1, kappa
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anti-Heat Shock 105kDa/110kDa Protein 1 (HSPH1) (AA 653-858) antibody
HSPH1 适用: 人 WB, IHC, ICC, IF, FACS 宿主: 小鼠 Monoclonal 3D10 unconjugated
anti-Heat Shock 105kDa/110kDa Protein 1 (HSPH1) (AA 653-858) antibodyHSPH1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, ICC, IF, FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Heat Shock 105kDa/110kDa Protein 1 (HSPH1) (AA 713-733) antibodyHSPH1 适用: 人, 大鼠, 小鼠 WB, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Heat Shock 105kDa/110kDa Protein 1 (HSPH1) antibodyKD Validated HSPH1 适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 23GB6190 unconjugated Recombinant Antibody
anti-Heat Shock 105kDa/110kDa Protein 1 (HSPH1) (AA 549-579) antibodyHSPH1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB16529 unconjugated
anti-Heat Shock 105kDa/110kDa Protein 1 (HSPH1) (C-Term) antibodyHSPH1 适用: 人, 大鼠, 小鼠 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Heat Shock 105kDa/110kDa Protein 1 (HSPH1) (C-Term) antibodyHSPH1 适用: 人, 小鼠 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Heat Shock 105kDa/110kDa Protein 1 (HSPH1) (AA 659-858) antibodyHSPH1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Heat Shock 105kDa/110kDa Protein 1 (HSPH1) antibodyKD Validated HSPH1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Heat Shock 105kDa/110kDa Protein 1 (HSPH1) antibodyHSPH1 适用: 人, 大鼠, 小鼠, 猴, Cow, Hamster, 绵羊, Saccharomyces cerevisiae WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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1. Optimal dilution of the HSPH1/Heat shock protein 105 kDa antibody should be determined by the researcher.
2. This HSPH1/Heat shock protein 105 kDa antibody is recombinantly produced by expression in CHO cells. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- HSPH1/Heat shock protein 105 kDa antibody with sodium azide - store at 2 to 8oC, antibody without sodium azide - store at -20 to -80oC.
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- HSPH1 (Heat Shock 105kDa/110kDa Protein 1 (HSPH1))
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别名
- HSPH1
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背景
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HSPH1 antibody is used to study Heat shock protein 105 kDa, a molecular chaperone involved in cellular stress responses and protein homeostasis. Heat shock protein 105 kDa is encoded by the HSPH1 gene and belongs to the HSP110 family of heat shock proteins, which function as nucleotide exchange factors for HSP70 chaperones. Through this activity, Heat shock protein 105 kDa supports protein folding, prevents aggregation of misfolded proteins, and helps maintain proteostasis under conditions of cellular stress.
Heat shock protein 105 kDa is also commonly referred to as HSP105 or HSP110 in the literature, reflecting its classification within the high-molecular-weight heat shock protein family. Unlike smaller heat shock proteins, HSPH1 exhibits strong ATP-dependent chaperone activity and plays an important role in stabilizing denatured proteins during heat shock and other stress conditions. Use of an HSPH1 antibody enables investigation of these stress-responsive chaperone functions in cell and tissue-based research models.
At the subcellular level, Heat shock protein 105 kDa localizes primarily to the cytoplasm, where it associates with protein complexes involved in folding and quality control. Under stress conditions, redistribution of HSPH1 has been reported, reflecting dynamic engagement with unfolded protein substrates. Studies using HSPH1 antibody have contributed to understanding how cells adapt to environmental stressors and maintain protein integrity through coordinated chaperone networks.
Altered expression of Heat shock protein 105 kDa has been examined in cancer biology and stress adaptation studies, where increased HSPH1 levels are often associated with enhanced cellular survival under proteotoxic stress. In tumor-derived cells, elevated HSPH1 expression is thought to support malignant growth by buffering protein-folding stress and stabilizing oncogenic signaling proteins. Detection of HSPH1 using an HSPH1 antibody supports research into stress tolerance, protein quality control, and cellular adaptation mechanisms in disease-associated contexts.
HSPH1 antibody (clone r58F12) is designed to detect Heat shock protein 105 kDa in research applications. Analysis of HSPH1 expression provides insight into chaperone-mediated protein folding, stress response pathways, and proteostasis regulation. Heat shock protein 105 kDa remains a key component of cellular defense mechanisms that protect against protein misfolding and stress-induced damage. -
UniProt
- Q92598
抗原
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