Recombinant ERG 抗体 (AA 1-300)
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北京 101111
Quick Overview for Recombinant ERG 抗体 (AA 1-300) (ABIN8093157)
抗原
See all ERG 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-300
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原理
- ERG Antibody / Erythroblast transformation specific related gene
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免疫原
- A recombinant fragment (around amino acids 1-300) of human ERG protein (exact sequence is proprietary) was used as the immunogen for the ERG/ERG transcription factor antibody.
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亚型
- IgG, kappa
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anti-ERG, ETS transcription factor (ERG) antibody
ERG 适用: 人 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 4H7 unconjugated
anti-ERG, ETS transcription factor (ERG) (C-Term) antibodyVerified ERG 适用: 人 WB, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-ERG, ETS transcription factor (ERG) (C-Term) antibodyERG 适用: 人, 小鼠 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-ERG, ETS transcription factor (ERG) antibodyERG 适用: 人, 犬 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 3E12 unconjugated
anti-ERG, ETS transcription factor (ERG) antibodyERG 适用: 人 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 5F12 unconjugated
anti-ERG, ETS transcription factor (ERG) antibodyERG 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-ERG, ETS transcription factor (ERG) (AA 1-160) antibodyERG 适用: 人 WB, IHC, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-ERG, ETS transcription factor (ERG) (AA 1-486) antibodyERG 适用: 人 IHC, ELISA, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-ERG, ETS transcription factor (ERG) antibodyERG 适用: 人, 小鼠 WB, IF 宿主: 小鼠 Monoclonal 5D10 unconjugated
anti-ERG, ETS transcription factor (ERG) (C-Term) antibodyERG 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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1. Optimal dilution of the ERG/ERG transcription factor antibody should be determined by the researcher.
2. This ERG/ERG transcription factor antibody is recombinantly produced by expression in CHO cells. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.05 % BSA, 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- ERG/ERG transcription factor antibody with sodium azide - store at 2 to 8oC, antibody without sodium azide - store at -20 to -80oC.
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- ERG (ERG, ETS transcription factor (ERG))
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别名
- ERG
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背景
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ERG antibody targets ERG transcription factor, a nuclear DNA-binding protein encoded by the ERG gene and a member of the ETS family of transcription factors. ERG functions as a sequence-specific regulator of gene expression and plays a central role in controlling cellular differentiation programs, lineage commitment, and maintenance of cell identity. Through transcriptional regulation, ERG influences diverse biological processes across vascular, hematopoietic, and developmental systems.
ERG transcription factor is localized to the nucleus, where it binds ETS consensus motifs within promoter and enhancer regions of target genes. Its activity is tightly regulated during development and in adult tissues, reflecting its importance in maintaining stable transcriptional states. ERG antibody detection is therefore useful for studying nuclear transcription factor expression and transcriptional network regulation in tissue-based and cell-based research models.
Functionally, ERG controls genes involved in cell survival, proliferation, and differentiation. In hematopoietic and progenitor cell populations, ERG supports lineage specification and self-renewal, while in endothelial and mesenchymal contexts it contributes to transcriptional programs governing structural and functional specialization. ERG antibody reagents support investigations into how transcription factors coordinate complex gene expression patterns underlying tissue development and homeostasis.
Dysregulation of ERG transcriptional activity has been implicated in multiple disease processes. Aberrant ERG expression or activation alters downstream gene networks and can contribute to pathological cell states, including malignant transformation and impaired differentiation. These transcriptional changes highlight the relevance of ERG antibody-based detection for research into disease-associated gene regulation and transcription factor dysfunction.
Clone ERG/9604R is designed to recognize ERG transcription factor in research applications. ERG antibody reagents are suitable for detecting nuclear ERG expression in diverse tissue types, supporting studies focused on transcriptional regulation, cell lineage biology, and disease-associated alterations in gene expression control. -
UniProt
- P11308
抗原
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