Recombinant ACPP 抗体 (full length)
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北京 101111
Quick Overview for Recombinant ACPP 抗体 (full length) (ABIN8092990)
抗原
See all ACPP 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- full length
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原理
- ACP3 Antibody / Prostatic acid phosphatase
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免疫原
- Recombinant full-length human ACPP3/PAP protein was used as the immunogen for the Prostatic Acid Phosphatase Antibody for IHC.
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亚型
- IgG1, kappa
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anti-Acid Phosphatase, Prostate (ACPP) (AA 40-300) antibody
ACPP 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Acid Phosphatase, Prostate (ACPP) (AA 56-215) antibodyACPP 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Acid Phosphatase, Prostate (ACPP) (AA 217-386) antibodyACPP 适用: 人 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Acid Phosphatase, Prostate (ACPP) (AA 150-386) antibodyACPP 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Acid Phosphatase, Prostate (ACPP) (Internal Region) antibodyVerified ACPP 适用: 人, 小鼠 WB, IHC, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Acid Phosphatase, Prostate (ACPP) antibodyACPP 适用: 人 IHC 宿主: 小鼠 Monoclonal rACPP-1338 unconjugated Recombinant Antibody
anti-Acid Phosphatase, Prostate (ACPP) (AA 1-386) antibodyACPP 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Acid Phosphatase, Prostate (ACPP) (AA 21-120) antibodyACPP 适用: 人 WB, IHC (p), IHC (fro), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Acid Phosphatase, Prostate (ACPP) antibodyACPP 适用: 人 FACS, cELISA 宿主: 小鼠 Monoclonal LT-3D1 unconjugated
anti-Acid Phosphatase, Prostate (ACPP) (AA 269-282) antibodyVerified ACPP 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
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应用备注
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1. Optimal dilution of the Prostatic Acid Phosphatase Antibody for IHC should be determined by the researcher.
2. This ACP3/Prostatic acid phosphatase antibody is recombinantly produced by expression in CHO cells.
3. Manual Protocol: Freshly cut sections should be used (less than 10 days between cutting and staining). Heat-induced antigen retrieval for 5 minutes in an autoclave at 121oC in pH 7.8 Target Retrieval Solution buffer. Apply the antibody at a dilution of 1:150 at 37oC for 60 minutes. Visualization of bound antibody by the EnVision Kit (Dako, Agilent) according to the manufacturer's directions. -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Antibody in 1X PBS with 0.05 % BSA, 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Prostatic Acid Phosphatase Antibody for IHC with sodium azide - store at 2 to 8oC, antibody without sodium azide - store at -20 to -80oC.
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- ACPP (Acid Phosphatase, Prostate (ACPP))
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别名
- ACP3
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背景
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Prostatic acid phosphatase (ACP3), also known as PAP, is a secreted phosphatase highly expressed in prostate epithelium and widely used as a biomarker in prostate cancer research and pathology. Prostatic Acid Phosphatase Antibody for IHC (clone MSVA-452M) recognizes this prostate-associated enzyme, which belongs to the histidine acid phosphatase family and participates in phosphomonoester hydrolysis. PAP is predominantly expressed in prostate epithelial cells and secreted into prostatic fluid, where it contributes to normal prostate physiology and enzymatic activity within the gland.
Prostatic Acid Phosphatase Antibody for IHC enables visualization of PAP protein expression in formalin-fixed paraffin-embedded tissues using immunohistochemistry. In IHC staining, PAP is typically detected in prostate epithelial cells where staining may appear cytoplasmic or luminal due to the secretory nature of the enzyme. This staining pattern reflects the physiological localization of prostatic acid phosphatase in glandular epithelial cells of the prostate and related secretory tissues.
Immunohistochemistry detection of prostatic acid phosphatase has long been used in studies of prostate biology and prostate cancer. PAP expression is strongly associated with prostate epithelial differentiation and is frequently evaluated in prostate carcinoma research. IHC staining using Prostatic Acid Phosphatase Antibody for IHC allows researchers to identify PAP-positive prostate epithelial cells and examine expression patterns in prostate tumors and metastatic lesions.
Prostatic acid phosphatase was historically used as one of the earliest biomarkers for prostate cancer prior to the introduction of PSA testing, and it continues to serve as a valuable marker of prostate epithelial differentiation. PAP expression can be observed in prostate glandular epithelium and prostate carcinoma cells, supporting studies of tumor differentiation and prostate tissue biology.
Prostatic Acid Phosphatase Antibody for IHC provides a research tool for detecting PAP expression in prostate tissues and prostate cancer models. Immunohistochemistry staining of ACP3 enables investigators to examine prostate epithelial differentiation, evaluate tumor cell phenotype in prostate carcinoma, and study the biological role of ACP3 in prostate tissue physiology and prostate cancer progression.
This ACP3 antibody is also part of a broader collection of < a href='/ihc-antibodies-tissue-microarray-validated.html'>IHC antibodies validated by tissue microarray analysis, supporting consistent staining across normal and cancer tissues. -
UniProt
- P15309
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途径
- Synaptic Membrane, Ribonucleoside Biosynthetic Process
抗原
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