PCDHGB5 抗体 (PE-Cy5)
Quick Overview for PCDHGB5 抗体 (PE-Cy5) (ABIN758483)
抗原
See all PCDHGB5 抗体适用
宿主
克隆类型
标记
应用范围
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预测反应
- Human,Mouse,Rat
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human PCDHGB5
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亚型
- IgG
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anti-Protocadherin gamma Subfamily B, 5 (PCDHGB5) (AA 283-373) antibody
PCDHGB5 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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FCM(1:100-500)
Optimal working dilution should be determined by the investigator. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- PCDHGB5 (Protocadherin gamma Subfamily B, 5 (PCDHGB5))
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别名
- PCDHGB5
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背景
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Synonyms: PCDH gamma B5, PCDHGB 5, Protocadherin gamma B5, Protocadherin gamma subfamily B 5, PCDGH_HUMAN.
Background: PCDHGB5 is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
抗原
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