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CASC3 抗体 (pTyr181) (Biotin)

CASC3 适用: 小鼠 WB, ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal Biotin
产品编号 ABIN757554
发货至: 中国
  • 抗原 See all CASC3 抗体
    CASC3 (Cancer Susceptibility Candidate 3 (CASC3))
    抗原表位
    • 15
    • 15
    • 9
    • 9
    • 8
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    pTyr181
    适用
    • 46
    • 35
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    小鼠
    宿主
    • 74
    • 1
    克隆类型
    • 75
    多克隆
    标记
    • 26
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    This CASC3 antibody is conjugated to Biotin
    应用范围
    • 65
    • 28
    • 27
    • 26
    • 26
    • 15
    • 5
    • 4
    • 4
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    小鼠
    预测反应
    Human,Rat,Cow,Pig,Horse,Chicken,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic phosphopeptide derived from human CASC3 around the phosphorylation site of Tyr181
    亚型
    IgG
    Top Product
    Discover our top product CASC3 Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    CASC3 (Cancer Susceptibility Candidate 3 (CASC3))
    别名
    CASC3 (CASC3 产品)
    别名
    BTZ antibody, MLN51 antibody, Btz antibody, Mln51 antibody, CASC3 antibody, btz antibody, mln51 antibody, StMLN51 antibody, barentsz antibody, XlMLN51 antibody, cancer susceptibility 3 antibody, cancer susceptibility candidate 3 antibody, protein CASC3 antibody, cancer susceptibility 3 S homeolog antibody, CASC3 antibody, Casc3 antibody, casc3 antibody, casc3.S antibody
    背景

    Synonyms: Barentsz protein, Btz, Cancer susceptibility candidate gene 3 protein, Metastatic lymph node protein 51, MLN 51 protein, MLN51, Protein barentsz, Protein CASC3, Protein MLN 51, CASC3_HUMAN.

    Background: The multiprotein exon junction complex (EJC) is deposited on mRNAs upstream of exonexon junctions as a consequence of pre-mRNA splicing. In mammalian cells, this complex serves as a key modulator of spliced mRNA metabolism. MLN51 is a nucleocytoplasmic shuttling protein that is overexpressed in breast cancer. The function of MLN51 in mammals remains elusive. Its fly homolog, named barentsz, as well as the proteins mago nashi and tsunagi have been shown to be required for proper oskar mRNA localization to the posterior pole of the oocyte. Magoh and Y14, the human homologs of mago nashi and tsunagi, are core components of the exon junction complex (EJC). The EJC is assembled on spliced mRNAs and plays important roles in post-splicing events including mRNA export, nonsense-mediated mRNA decay, and translation. Human MLN51 is an RNA-binding protein present in ribonucleo-protein complexes.

    基因ID
    22794
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