Vip 抗体
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北京 101111
Quick Overview for Vip 抗体 (ABIN8065532)
抗原
See all Vip 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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原理
- Anti-Vasoactive Intestinal Peptide Antibody
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特异性
- ABS 023-02 binds to human, bovine, porcine or rat VIP, but does not bind to PHM or PACAP.
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预测反应
- Bovine,Human,Pig,and Rat
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纯化方法
- Protein A or Protein G purified
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免疫原
- Vasoactive intestinal peptide
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亚型
- IgG1, kappa
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anti-Vasoactive Intestinal Peptide (Vip) (AA 34-157) antibody
Vip 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Vasoactive Intestinal Peptide (Vip) (Middle Region) antibodyVip 适用: 人, 大鼠, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Vasoactive Intestinal Peptide (Vip) (AA 28-159) antibodyVip 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Vasoactive Intestinal Peptide (Vip) (AA 139-167) antibodyVip 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Vasoactive Intestinal Peptide (Vip) (AA 139-167), (C-Term) antibodyVip 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB18839 unconjugated
anti-Vasoactive Intestinal Peptide (Vip) antibodyVip 适用: 人, 大鼠, 小鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Vasoactive Intestinal Peptide (Vip) (AA 125-152) antibodyVip 适用: 人 IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Vasoactive Intestinal Peptide (Vip) (AA 31-170) antibodyVip 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Vasoactive Intestinal Peptide (Vip) (Internal Region) antibodyVip 适用: 人, 大鼠, 小鼠 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Vasoactive Intestinal Peptide (Vip) antibodyVip 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- 2-8°C without exposure to light
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有效期
- 24 months
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- Vip (Vasoactive Intestinal Peptide (Vip))
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别名
- Vasoactive Intestinal Peptide
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背景
- VIP, PHM27, VIP peptides, prepro-VIP,[Vasoactive intestinal peptide]: VIP is a neuropeptide involved in a diverse array of physiological processes through activating the PACAP subfamily of class B1 G protein-coupled receptors: VIP receptor 1 (VPR1) and VIP receptor 2 (VPR2) (PubMed:1318039, PubMed:36385145, PubMed:8933357). Abundantly expressed throughout the CNS and peripheral nervous systems where they primarily exert neuroprotective and immune modulatory roles (PubMed:3456568). Also causes vasodilation, lowers arterial blood pressure, stimulates myocardial contractility, increases glycogenolysis and relaxes the smooth muscle of trachea, stomach and gall bladder (PubMed:15013843). {ECO:0000269|PubMed:1318039, ECO:0000269|PubMed:15013843, ECO:0000269|PubMed:3456568, ECO:0000269|PubMed:36385145, ECO:0000269|PubMed:8933357}., [Intestinal peptide PHM-27]: Bioactive forms that cause vasodilation (PubMed:15013843, PubMed:3654650). PHM-27 is a potent agonist of the calcitonin receptor CALCR, with similar efficacy as calcitonin (PubMed:15013843). {ECO:0000269|PubMed:15013843, ECO:0000269|PubMed:3654650}., [Intestinal peptide PHV-42]: Bioactive forms that cause vasodilation (PubMed:15013843, PubMed:3654650). {ECO:0000269|PubMed:15013843, ECO:0000269|PubMed:3654650}.,VIP,Vasoactive intestinal peptide (VIP) is a 28 amino acid peptide belonging to the secretin-glucagon family of peptide hormones. Its sequence is identical in humans, cows, pigs and rats. VIP is widely distributed in the central and peripheral nervous systems, acting as a neurotransmitter or neuromodulator. Peripherally it is involved in vaso- and bronchodilatation, smooth muscle relaxation and stimulation of secretion. Ectopic endocrine tumors secreting VIP (VIPomas) give rise to raised plasma levels of VIP and are associated with watery diarrhea, hypokalemia and achlorhydria syndrome. VIP shows high sequence homology with peptide histidine-methionine (PHM) in humans or peptide histidine-serine (PHI) in pigs or rats, present in the same precursor, and with the neuropeptide pituitary adenylate cyclase activating polypeptide (PACAP).
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分子量
- 16 kDa (recombinant/precursor), 4 kDa (native/active)
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基因ID
- 7432
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UniProt
- P01282
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途径
- Hormone Activity, cAMP Metabolic Process
抗原
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