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PAEP 抗体

The 小鼠 单克隆 anti-PAEP antibody is suitable to detect PAEP in samples from 人. It has been validated for ELISA 和 IHC.
产品编号 ABIN8065527
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for PAEP 抗体 (ABIN8065527)

抗原

See all PAEP 抗体
PAEP (Progestagen-Associated Endometrial Protein (PAEP))

适用

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宿主

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小鼠

克隆类型

  • 58
  • 19
单克隆

标记

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This PAEP antibody is un-conjugated

应用范围

  • 42
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ELISA, Immunohistochemistry (IHC)

质量等级

Carrier-free

克隆位点

16
  • 原理

    Anti-Placental Protein 14 Antibody

    特异性

    BTE 001-16 is specific for human PP14 protein 14 (human, PP14, glycodelin A). Epitode differs from BTE 001-13

    预测反应

    Human

    纯化方法

    Protein A or Protein G purified

    免疫原

    Placental protein 14 (glycodelin A) purified from second trimester amniotic fluid

    亚型

    IgG1, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    2-8°C without exposure to light

    有效期

    24 months
  • 抗原

    PAEP (Progestagen-Associated Endometrial Protein (PAEP))

    别名

    Placental Protein 14

    背景

    PAEP, GD, GdA, GdF, GdS, PAEG, PEP, PP14, ZIF-1, glycodelin, PEG, PP14 protein (placental protein 14), alpha uterine protein, glycodelin-A, glycodelin-F, glycodelin-S, placental protein 14, pregnancy-associated endometrial alpha-2 globulin, progestagen-associated endometrial protein (placental protein 14, pregnancy-associated endometrial a, progesterone-associated endometrial protein, zona-binding inhibitory factor-1,Glycoprotein that regulates critical steps during fertilization and also has immunomonomodulatory effects. Four glycoforms, namely glycodelin-S, -A, -F and -C have been identified in reproductive tissues that differ in glycosylation and biological activity. Glycodelin-A has contraceptive and immunosuppressive activities (PubMed:7531163, PubMed:9918684). Glycodelin-C stimulates binding of spermatozoa to the zona pellucida (PubMed:17192260). Glycodelin-F inhibits spermatozoa-zona pellucida binding and significantly suppresses progesterone-induced acrosome reaction of spermatozoa (PubMed:12672671). Glycodelin-S in seminal plasma maintains the uncapacitated state of human spermatozoa (PubMed:15883155). {ECO:0000269|PubMed:12672671, ECO:0000269|PubMed:15883155, ECO:0000269|PubMed:17192260, ECO:0000269|PubMed:7531163, ECO:0000269|PubMed:9918684}.,PAEP,Human placental protein 14 (PP14, also known as glycodelin and progesterone-associated endometrial protein) is a protein of the lipocalin structural superfamily. PP14 is the most abundant product of the secretory endometrium, and has been proposed as a biochemical marker of endometrial function in women undergoing in vitro fertilization treatment. (1)

    分子量

    20 kDa

    基因ID

    5047

    UniProt

    P09466
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