PAEP 抗体
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北京 101111
Quick Overview for PAEP 抗体 (ABIN8065526)
抗原
See all PAEP 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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原理
- Anti-Placental Protein 14 Antibody
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特异性
- BTE 001-13 is specific for human PP14. Differs from BTE 001-16
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预测反应
- Human
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纯化方法
- Protein A or Protein G purified
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免疫原
- Placental protein 14 (glycodelin A) purified from second trimester amniotic fluid
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亚型
- IgG1, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- 2-8°C without exposure to light
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有效期
- 24 months
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- PAEP (Progestagen-Associated Endometrial Protein (PAEP))
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别名
- Placental Protein 14
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背景
- PAEP, GD, GdA, GdF, GdS, PAEG, PEP, PP14, ZIF-1, glycodelin, PEG, PP14 protein (placental protein 14), alpha uterine protein, glycodelin-A, glycodelin-F, glycodelin-S, placental protein 14, pregnancy-associated endometrial alpha-2 globulin, progestagen-associated endometrial protein (placental protein 14, pregnancy-associated endometrial a, progesterone-associated endometrial protein, zona-binding inhibitory factor-1,Glycoprotein that regulates critical steps during fertilization and also has immunomonomodulatory effects. Four glycoforms, namely glycodelin-S, -A, -F and -C have been identified in reproductive tissues that differ in glycosylation and biological activity. Glycodelin-A has contraceptive and immunosuppressive activities (PubMed:7531163, PubMed:9918684). Glycodelin-C stimulates binding of spermatozoa to the zona pellucida (PubMed:17192260). Glycodelin-F inhibits spermatozoa-zona pellucida binding and significantly suppresses progesterone-induced acrosome reaction of spermatozoa (PubMed:12672671). Glycodelin-S in seminal plasma maintains the uncapacitated state of human spermatozoa (PubMed:15883155). {ECO:0000269|PubMed:12672671, ECO:0000269|PubMed:15883155, ECO:0000269|PubMed:17192260, ECO:0000269|PubMed:7531163, ECO:0000269|PubMed:9918684}.,PAEP,Human placental protein 14 (PP14, also known as glycodelin and progesterone-associated endometrial protein) is a protein of the lipocalin structural superfamily. PP14 is the most abundant product of the secretory endometrium, and has been proposed as a biochemical marker of endometrial function in women undergoing in vitro fertilization treatment (1).
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分子量
- 20 kDa
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基因ID
- 5047
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UniProt
- P09466
抗原
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