Peptide YY 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for Peptide YY 抗体 (N-Term) (ABIN8065519)
抗原
See all Peptide YY (PYY) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
-
-
抗原表位
- N-Term
-
原理
- Anti-PYY (3-36) (peptide tyrosine-tyrosine amide, 3-36) Antibody
-
特异性
- ABIN8065519 binds human PYY(3-36). Based on inhibition ELISA, ABIN8065519 shows no cross-reaction with PYY(1-36) or NPY. The epitope lies within residues 3-12 of human PYY.
-
预测反应
- Human
-
纯化方法
- Protein A or Protein G purified
-
免疫原
- Synthetic N-terminal fragment of human PYY(3-36) coupled to carrier.
-
亚型
- IgG2a, kappa
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- 0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
储存方法
- 2-8°C without exposure to light
-
有效期
- 24 months
-
-
- Peptide YY (PYY)
-
别名
- PYY
-
背景
- PYY, PYY-I, PYY1, peptide YY, peptide tyrosine tyrosine, prepro-PYY,This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility.,PYY,Peptide tyrosine-tyrosine amide (3-36), or PYY(3-36), is a major metabolite of the gut hormone PYY and is produced by the action of dipeptidyl peptidase IV on PYY in the intestinal brush border and in the circulation. PYY(3-36) is a potent inhibitor of food intake in rats and humans, acting selectively on the Y2 receptor to inhibit orexigenic NPY neurons in the arcuate nucleus, thus disinhibiting anorexigenic POMC neurons. The anorexigenic effect of PYY(3-36) is additive to that of the co-secreted gut hormone GLP-1.
-
分子量
- 4 kDa
-
基因ID
- 5697
-
UniProt
- P10082
抗原
-