GLP-1 抗体 (N-Term)
The 小鼠 单克隆 anti-GLP-1 antibody (Clone 1E1) (ABIN8065489) specifically detects GLP-1 in WB 和 ELISA.
The antibody is reactive with 人 samples.
产品编号 ABIN8065489
发货至:
中国
Contact our Customer Service for availability and price in your country.
Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for GLP-1 抗体 (N-Term) (ABIN8065489)
抗原
See all GLP-1 抗体
GLP-1
(Glucagon-like peptide 1 (GLP-1))
适用
人
宿主
小鼠
克隆类型
单克隆
标记
This GLP-1 antibody is un-conjugated
应用范围
Western Blotting (WB), ELISA
质量等级
Carrier-free
克隆位点
1E1
-
-
抗原表位
- N-Term
-
原理
- Anti-GLP-1 (7-37) and GLP-1 (7-36) amide (N-term) Antibody
-
特异性
- ABS 033-10 binds the free N-terminus of GLP-1(7-37) and GLP-1(7-36)amide and shows <0.2 % cross-reactivity with GLP-1(9-36)amide, glucagon and human GIP. Cross-reacts 0.25 % with GLP-1(1-37), approximately 6 % with human GLP-2 and approximately 50 % with exendin-4. ABS 033-10 cross-reacts with Liraglutide.
-
预测反应
- Human
-
纯化方法
- Protein A or Protein G purified
-
免疫原
- Synthetic GLP-1(7-17)
-
亚型
- IgG2a, kappa
-
-
anti-Glucagon-like peptide 1 (GLP-1) (AA 7-36) antibody
GLP-1 适用: 人 IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Glucagon-like peptide 1 (GLP-1) (AA 1-31) antibodyGLP-1 适用: 人, 小鼠, 大鼠 IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- 0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
储存方法
- 2-8°C without exposure to light
-
有效期
- 24 months
-
-
- GLP-1 (Glucagon-like peptide 1 (GLP-1))
-
别名
- GLP-1
-
背景
- GCG, GLP-1, GLP1, GLP2, GRPP, pro-glucagon, glicentin-related polypeptide, glucagon-like peptide 1, glucagon-like peptide 2, incretin, preproglucagon,Glucagon-like peptide 1. Potent stimulator of glucose-dependent insulin release (PubMed:22037645, PubMed:40446798). Also stimulates insulin release in response to IL6 (PubMed:22037645). Plays important roles on gastric motility and the suppression of plasma glucagon levels (PubMed:10605628, PubMed:14719035, PubMed:12554744). May be involved in the suppression of satiety and stimulation of glucose disposal in peripheral tissues, independent of the actions of insulin (PubMed:10605628, PubMed:14719035, PubMed:12554744). Has growth-promoting activities on intestinal epithelium (PubMed:10605628, PubMed:14719035, PubMed:12554744). May also regulate the hypothalamic pituitary axis (HPA) via effects on LH, TSH, CRH, oxytocin, and vasopressin secretion (PubMed:10605628, PubMed:14719035, PubMed:12554744). Increases islet mass through stimulation of islet neogenesis and pancreatic beta cell proliferation (PubMed:10605628, PubMed:14719035, PubMed:12554744). Inhibits beta cell apoptosis (PubMed:10605628, PubMed:14719035, PubMed:12554744).,GCG,Glucagon-like peptide 1(7-36)amide (GLP-1(7-36)amide) is the principal active form of GLP-1, the other being GLP-1(7-37). GLP-1 is a peptide hormone of the glucagon family, produced by the L cells of the intestinal mucosa from the same prohormone as glucagon. The active forms are potent stimulators of glucose-dependent insulin secretion. The sequence of GLP-1 is fully conserved in all mammalian species examined so far.
-
分子量
- 20 kDa (proglucagon)
-
基因ID
- 2641
-
UniProt
- P01275
抗原
-
You are here:
