Glucagon 抗体 (N-Term)
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Quick Overview for Glucagon 抗体 (N-Term) (ABIN8065485)
抗原
See all Glucagon (GCG) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- N-Term
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原理
- Anti-Glucagon Antibody
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特异性
- ABS 058-08 binds human glucagon. The epitope lies within the N-terminal half of human glucagon
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预测反应
- Human,Pig,and Rat
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纯化方法
- Protein A or Protein G purified
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免疫原
- Synthetic N-terminal fragment of glucagon coupled to carrier
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亚型
- IgG1, kappa
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anti-Glucagon (GCG) (AA 119-148), (C-Term) antibody
GCG 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB19525 unconjugated
anti-Glucagon (GCG) antibodyGCG 适用: 人 WB, IHC, ELISA, IF, FM 宿主: 兔 Polyclonal unconjugated
anti-Glucagon (GCG) (AA 21-180) antibodyGCG 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glucagon (GCG) antibodyGCG 适用: 人 IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Glucagon (GCG) (AA 1-180) antibodyGCG 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E2-E6 unconjugated
anti-Glucagon (GCG) (AA 25-54), (N-Term) antibodyGCG 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB19443 unconjugated
anti-Glucagon (GCG) (N-Term) antibodyGCG 适用: 人, 大鼠, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Glucagon (GCG) (AA 53-81) antibodyGCG 适用: 人 IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Glucagon (GCG) (AA 23-180) antibodyGCG 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glucagon (GCG) (AA 1-180) antibodyGCG 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- 2-8°C without exposure to light
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有效期
- 24 months
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- Glucagon (GCG)
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别名
- Glucagon
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背景
- GCG, GLP-1, GLP1, GLP2, GRPP, pro-glucagon, glicentin-related polypeptide, glucagon-like peptide 1, glucagon-like peptide 2, incretin, preproglucagon,Glucagon-like peptide 1. Potent stimulator of glucose-dependent insulin release (PubMed:22037645, PubMed:40446798). Also stimulates insulin release in response to IL6 (PubMed:22037645). Plays important roles on gastric motility and the suppression of plasma glucagon levels (PubMed:10605628, PubMed:14719035, PubMed:12554744). May be involved in the suppression of satiety and stimulation of glucose disposal in peripheral tissues, independent of the actions of insulin (PubMed:10605628, PubMed:14719035, PubMed:12554744). Has growth-promoting activities on intestinal epithelium (PubMed:10605628, PubMed:14719035, PubMed:12554744). May also regulate the hypothalamic pituitary axis (HPA) via effects on LH, TSH, CRH, oxytocin, and vasopressin secretion (PubMed:10605628, PubMed:14719035, PubMed:12554744). Increases islet mass through stimulation of islet neogenesis and pancreatic beta cell proliferation (PubMed:10605628, PubMed:14719035, PubMed:12554744). Inhibits beta cell apoptosis (PubMed:10605628, PubMed:14719035, PubMed:12554744).,GCG,Glucagon is a peptide hormone of 29 amino-acid residues produced by the alpha cells of the pancreatic islets. Its effect is to raise blood sugar as a stress hormone and counter-regulatory hormone for insulin. It is produced by cell-type-specific processing of proglucagon, which in the alpha cells is split to form glicentin-related pancreatic polypeptide, glucagon and major proglucagon fragment, while the same precursor is split to form glicentin, oxyntomodulin (C-terminally extended glucagon-37), GLP-1 and GLP-2 in the L cells of the intestinal mucosa.
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分子量
- 20.4 kDa
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基因ID
- 2641
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UniProt
- P01275
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途径
- Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Negative Regulation of intrinsic apoptotic Signaling
抗原
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