Ghrelin 抗体
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北京 101111
Quick Overview for Ghrelin 抗体 (ABIN8065475)
抗原
See all Ghrelin (GHRL) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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原理
- Anti-Ghrelin Antibody
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特异性
- ABS 050-45 binds human octanoylated ghrelin and human des-acyl ghrelin.
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预测反应
- Human,Rat
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纯化方法
- Protein A or Protein G purified
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免疫原
- Synthetic human Ser3-octanoyl ghrelin-28
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亚型
- IgG1, lambda
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anti-Ghrelin (GHRL) (AA 1-117) antibody
GHRL 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2F4 unconjugated
anti-Ghrelin (GHRL) (AA 28-117) antibodyGHRL 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ghrelin (GHRL) antibodyGHRL 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ghrelin (GHRL) (AA 25-117) antibodyGHRL 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ghrelin (GHRL) (C-Term) antibodyVerified GHRL 适用: 人, 大鼠 IHC, ELISA, ICC 宿主: 山羊 Polyclonal unconjugated
anti-Ghrelin (GHRL) (AA 31-117) antibodyGHRL 适用: 人 WB, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Ghrelin (GHRL) (AA 24-117) antibodyGHRL 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2F2 unconjugated
anti-Ghrelin (GHRL) (AA 1-118) antibodyGHRL 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2F4 unconjugated
anti-Ghrelin (GHRL) (AA 1-117) antibodyGHRL 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ghrelin (GHRL) (Internal Region) antibodyGHRL 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- 2-8°C without exposure to light
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有效期
- 24 months
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- Ghrelin (GHRL)
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别名
- Ghrelin
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背景
- GHRL, MTLRP, appetite-regulating hormone, In2c-preproghrelin, ghrelin, growth hormone secretagogue receptor ligand, ghrelin/obestatin preprohormone, ghrelin/obestatin prepropeptide, growth hormone-releasing peptide, motilin-related peptide, prepro-appetite regulatory hormone, preproghrelin,Precursor of the appetite-regulating peptide ghrelin, including ghrelin-27 and ghrelin-28. {ECO:0000269|PubMed:11306336, ECO:0000269|PubMed:35027551}., [Ghrelin-27]: Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR) (PubMed:10604470, PubMed:35027551). Induces the release of growth hormone from the pituitary (PubMed:10604470). Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation. {ECO:0000269|PubMed:10604470, ECO:0000269|PubMed:35027551}., [Ghrelin-28]: Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR) (PubMed:10604470, PubMed:35027551). Octanoylated ghrelin-28 is the most commonly found ghrelin and octanoylation is essential for the activation of the growth hormone secretagogue receptor type 1 (GHSR) (PubMed:11306336, PubMed:35027551). Induces the release of growth hormone from the pituitary (PubMed:10604470). Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation. {ECO:0000269|PubMed:10604470, ECO:0000269|PubMed:11306336, ECO:0000269|PubMed:35027551}., [Obestatin]: May be the ligand for GPR39. May have an appetite-reducing effect resulting in decreased food intake. May reduce gastric emptying activity and jejunal motility (By similarity). {ECO:0000250}.,GHRL,Ghrelin is an orexigenic (food intake stimulating) 27 or 28 amino-acid gut-brain peptide hormone produced by endocrine cells in the stomach, pancreatic islets and certain hypothalamic neurons. Two forms are produced by alternative mRNA splicing, Gln13 or 14 is missing from the second form. "Active" ghrelin is acylated (octanoylated) at Ser3, this form stimulates growth hormone secretion via GHS receptors and increases appetite. The des-acyl form does not have these effects but may have other actions. Plasma responses of total ghrelin to food may reflect those of active ghrelin.
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分子量
- 13 kDa (pro-ghrelin), 6 kDa (mature ghrelin)
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基因ID
- 51738
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UniProt
- Q9UBU3
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途径
- Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Peptide Hormone Metabolism, Negative Regulation of Hormone Secretion, Synaptic Membrane, Feeding Behaviour
抗原
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