Exendin 4 抗体
The 小鼠 单克隆 anti-Exendin 4 antibody is suitable to detect Exendin 4 in samples from Gila monster. It has been validated for ELISA.
产品编号 ABIN8065455
发货至:
中国
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Contact Info
Our Local Distributor
中国
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北京 101111
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Quick Overview for Exendin 4 抗体 (ABIN8065455)
抗原
See all Exendin 4 抗体
Exendin 4
适用
Gila monster
宿主
小鼠
克隆类型
单克隆
标记
This Exendin 4 antibody is un-conjugated
应用范围
ELISA
质量等级
Carrier-free
克隆位点
2E1
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原理
- Anti-Exendin-4 Antibody
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特异性
- Specific for exendin-4. No cross-reactivity with GLP-1, GLP-2 (human) or glucagon coated on ELISA wells. The epitope is in the 9-39 region of the peptide, and the antibody cross-reacts strongly with exendin (9-39) amide.
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预测反应
- Gila monster Heloderma suspectum
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纯化方法
- Protein A or Protein G purified
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免疫原
- Synthetic exendin-4
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亚型
- IgG1, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- 2-8°C without exposure to light
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有效期
- 24 months
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- Exendin 4
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别名
- Exendin-4
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背景
- Exenatide,Venom protein that mimics the incretin hormone glucagon-like peptide 1 (GLP-1). It stimulates insulin synthesis and secretion, protects against beta-cell apoptosis in response to different insults, and promotes beta-cell proliferation. It also promotes satiety, reduces food intake, reduces fat deposition, reduces body weight and inhibits gastric emptying. Interacts with GLP-1 receptor (GLP1R). Induces hypotension that is mediated by relaxation of cardiac smooth muscle.,N/A,Exendin-4 is a 39 amino acid peptide found in venom from the Gila monster Heloderma suspectum. It is a member of the glucagon-secretin family of peptide hormones and neuropeptides. Exendin-4 is a potent agonist of the GLP-1 receptor and hence a potent stimulator of insulin secretion.
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分子量
- 4.2 kDa
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UniProt
- P26349
抗原
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