D-Dimer 抗体
This 小鼠 单克隆 antibody specifically detects D-Dimer in ELISA 和 WB. It exhibits reactivity toward 人.
产品编号 ABIN8065445
发货至:
中国
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Contact Info
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中国
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北京 101111
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Quick Overview for D-Dimer 抗体 (ABIN8065445)
抗原
See all D-Dimer 抗体
D-Dimer
适用
人
宿主
小鼠
克隆类型
单克隆
标记
This D-Dimer antibody is un-conjugated
应用范围
ELISA, Western Blotting (WB)
质量等级
Carrier-free
克隆位点
22
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原理
- Anti-D-Dimer Antibody
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特异性
- ABS 015-22 binds human D-dimer. Cross-reacts < 2 % with directly coated D-monomer but not with directly coated fibrinogen. When tested in a pair with itself, with ABS 015-28 and with a fibrinogen-specific polyclonal antibody, the epitope appears to relate to the dimerization site of D-dimer.
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预测反应
- Canine,Human
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纯化方法
- Protein A or Protein G purified
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免疫原
- Purified human D-dimer
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亚型
- IgG1, kappa
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anti-D-Dimer antibody
适用: 人 ELISA, WB, PrA 宿主: 小鼠 Monoclonal DD1 unconjugated
anti-D-Dimer antibody适用: 人 ELISA, Aggl, LA 宿主: 兔 Chimeric 3B6 unconjugated Recombinant Antibody
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- 2-8°C without exposure to light
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有效期
- 24 months
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- D-Dimer
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背景
- FGA, AMYLD2, Fib2, fibrinogen alpha chain, fibrinogen, A alpha polypeptide, FGB, HEL-S-78p, fibrinogen beta chain, beta-fibrinogen, epididymis secretory sperm binding protein Li 78p, fibrinogen, B beta polypeptide, FGG, fibrinogen gamma chain, fibrinogen, gamma polypeptide, testicular tissue protein Li 70,Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the immune response via both innate and T-cell mediated pathways,FGA, FGB, FGG,D-dimer is a fibrin degradation product, a small protein fragment present in the blood after a blood clot is degraded by fibrinolysis.
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分子量
- 180 kDa
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基因ID
- 2243, 2244, 2266
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UniProt
- P02671, P02675, P02679
抗原
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