DDIT3 抗体 (pSer30)
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- 抗原 See all DDIT3 抗体
- DDIT3 (DNA-Damage-Inducible Transcript 3 (DDIT3))
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抗原表位
- pSer30
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DDIT3 antibody is un-conjugated
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应用范围
- ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人, 大鼠
- 预测反应
- Mouse,Dog,Cow,Sheep,Pig,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic phosphopeptide derived from human GADD153 around the phosphorylation site of Ser30
- 亚型
- IgG
- Top Product
- Discover our top product DDIT3 Primary Antibody
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- 应用备注
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ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- DDIT3 (DNA-Damage-Inducible Transcript 3 (DDIT3))
- 别名
- GADD153 (DDIT3 产品)
- 别名
- chop antibody, Xchop antibody, cebpz antibody, chop10 antibody, gadd153 antibody, CHOP-10 antibody, CHOP10 antibody, CHOP antibody, Chop10 antibody, Gadd153 antibody, CEBPZ antibody, GADD153 antibody, DNA damage inducible transcript 3 antibody, DNA-damage inducible transcript 3 antibody, DNA damage inducible transcript 3 L homeolog antibody, ddit3 antibody, Ddit3 antibody, DDIT3 antibody, ddit3.L antibody
- 背景
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Synonyms: Growth arrest and DNA damage-inducible 153, C/EBP homologous protein, C/EBP Homology Protein, CEBPZ, CHOP 10, CHOP, CHOP10, DDIT 3, DDIT3, DNA Damage Inducible Transcript 3, GADD 153, Growth Arrest and DNA Damage Inducible Protein 153, Growth arrest and DNA damage inducible protein GADD153, MGC4154, DDIT3_HUMAN.
Background: This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified.
- 基因ID
- 1649
- 途径
- Regulation of Muscle Cell Differentiation, ER-Nucleus Signaling, Skeletal Muscle Fiber Development, Cell RedoxHomeostasis
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