Zona Pellucida Glycoprotein 3 抗体 (Middle Region) (APC)
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Quick Overview for Zona Pellucida Glycoprotein 3 抗体 (Middle Region) (APC) (ABIN8055368)
抗原
See all Zona Pellucida Glycoprotein 3 (ZP3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- Anti-ZP3 Antibody APC Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human ZP3, which shares 77.4% amino acid (aa) sequence identity with both mouse and rat ZP3.
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亚型
- IgG
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anti-Zona Pellucida Glycoprotein 3 (ZP3) (AA 250-350) antibody
ZP3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Zona Pellucida Glycoprotein 3 (ZP3) (AA 353-380), (C-Term) antibodyZP3 适用: 人 WB 宿主: 兔 Polyclonal RB36988 unconjugated
anti-Zona Pellucida Glycoprotein 3 (ZP3) (AA 1-373) antibodyZP3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Zona Pellucida Glycoprotein 3 (ZP3) (C-Term) antibodyZP3 适用: 人, Cow, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- Zona Pellucida Glycoprotein 3 (ZP3)
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别名
- ZP3
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背景
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Background: Zona pellucida sperm-binding protein 3, also known as zona pellucida glycoprotein 3 (Zp-3) or the sperm receptor, is a ZP module-containing protein that in humans is encoded by the ZP3 gene. It is mapped to 7q11.23. he zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The protein encoded by this gene is a structural component of the zona pellucida and functions in primary binding and induction of the sperm acrosome reaction. The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a C-terminal consensus furin cleavage site, and a transmembrane domain. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on mouse studies. A variation in the last exon of this gene has previously served as the basis for an additional ZP3 locus, however, sequence and literature review reveals that there is only one full-length ZP3 locus in the human genome. Another locus encoding a bipartite transcript designated POMZP3 contains a duplication of the last four exons of ZP3, including the above described variation, and maps closely to this gene.
Gene Full Name: zona pellucida glycoprotein 3
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基因ID
- 7784
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UniProt
- P21754
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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