ZBTB48 抗体 (AA 1-623) (PE)
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北京 101111
Quick Overview for ZBTB48 抗体 (AA 1-623) (PE) (ABIN8055116)
抗原
See all ZBTB48 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-623
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原理
- Anti-ZBTB48 Antibody PE Conjugated
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交叉反应 （详细）
- No cross-reactivity with other proteins
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human ZBTB48 recombinant protein (Position: M1-M623).
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亚型
- IgG
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anti-Zinc Finger and BTB Domain Containing 48 (ZBTB48) (AA 1-688) antibody
ZBTB48 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Zinc Finger and BTB Domain Containing 48 (ZBTB48) (AA 1-280) antibodyZBTB48 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger and BTB Domain Containing 48 (ZBTB48) (AA 468-517) antibodyZBTB48 适用: 人, 小鼠, 大鼠, 犬, 马, 兔, 豚鼠, Cow, 猴, Bat, 小鸡, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger and BTB Domain Containing 48 (ZBTB48) (AA 144-193) antibodyZBTB48 适用: 人, 犬, 马, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger and BTB Domain Containing 48 (ZBTB48) (AA 1-280) antibodyZBTB48 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger and BTB Domain Containing 48 (ZBTB48) (N-Term) antibodyZBTB48 适用: 人, 小鼠, 大鼠, 犬, 马, 兔, 豚鼠, Cow, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger and BTB Domain Containing 48 (ZBTB48) (N-Term) antibodyZBTB48 适用: 人, 小鼠, 大鼠, 犬, 马, 兔, 豚鼠, Cow WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- ZBTB48 (Zinc Finger and BTB Domain Containing 48 (ZBTB48))
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别名
- ZBTB48
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背景
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Background: Zinc finger and BTB domain containing 48 (ZBTB48), also known as telomeric zinc-finger associated protein (TZAP), is a protein that ly binds to the double-stranded repeat sequence of telomeres. In humans it is encoded by the ZBTB48 gene. ZBTB48, also named as TZAP and HKR3, is a 688 amino acid protein, which contains 1 BTB (POZ) domain and 11 C2H2-type zinc fingers and belongs to the krueppel C2H2-type zinc-finger protein family. ZBTB48 is detected in adrenal gland and neuroblastoma. ZBTB48 binds to and regulates the J and/or S elements in MHC II promoter. Zinc finger and BTB domain containing 48 (ZBTB48), also known as telomeric zinc-finger associated protein (TZAP), is a protein that triggers the trimming of telomeres in the absence of shelterin. ZBTB48, is a relatively uncharacterized POK family protein with a POZ-domain and 11 zinc finger domains. ZBTB48, is ubiquitously expressed in human tissues. The ZBTB48 gene is mapped to human chromosome 1p36, which is commonly rearranged (leiomyoma and leukemias) or deleted in various cancers (neuroblastoma, melanoma, Merkel cell carcinomas, pheochromocytoma and breast and colon carcinomas. A correlation between deletions or rearrangements of HKR3 and human cancer suggest a role for ZBTB48 as a potential tumor suppressor.
Gene Full Name: zinc finger and BTB domain containing 48
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基因ID
- 3104
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UniProt
- P10074
抗原
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