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WWOX 抗体 (AA 1-245) (HRP)

This 小鼠 单克隆 antibody specifically detects WWOX in WB, ELISA 和 IHC. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN8054552
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for WWOX 抗体 (AA 1-245) (HRP) (ABIN8054552)

抗原

See all WWOX 抗体
WWOX (WW Domain Containing Oxidoreductase (WWOX))

适用

  • 89
  • 71
  • 33
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 83
  • 13
  • 1
小鼠

克隆类型

  • 74
  • 23
单克隆

标记

  • 46
  • 7
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
This WWOX antibody is conjugated to HRP

应用范围

  • 61
  • 32
  • 29
  • 23
  • 16
  • 15
  • 7
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

克隆位点

3D10
  • 抗原表位

    • 23
    • 12
    • 9
    • 8
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-245

    原理

    Anti-WWOX Antibody (monoclonal, 3D10) HRP Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E. coli-derived human WWOX recombinant protein (Position: M1-D245).

    亚型

    IgG1
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    WWOX (WW Domain Containing Oxidoreductase (WWOX))

    别名

    WWOX

    背景

    Background: WW domain-containing oxidoreductase is an enzyme that in humans is encoded by the WWOX gene. This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) protein family. It spans the FRA16D common chromosomal fragile site and appears to function as a tumor suppressor gene. Expression of the encoded protein is able to induce apoptosis, while defects in this gene are associated with multiple types of cancer. Disruption of this gene is also associated with autosomal recessive spinocerebellar ataxia 12. Disruption of a similar gene in mouse results in impaired steroidogenesis, additionally suggesting a metabolic function for the protein. Alternative splicing results in multiple transcript variants.

    Gene Full Name: WW domain containing oxidoreductase

    基因ID

    51741

    UniProt

    Q9NZC7
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