WFS1 抗体 (AA 272-876) (HRP)
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北京 101111
Quick Overview for WFS1 抗体 (AA 272-876) (HRP) (ABIN8054508)
抗原
See all WFS1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 272-876
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原理
- Anti-WFS1 Antibody HRP Conjugated
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human WFS1 recombinant protein (Position: D272-K876).
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亚型
- IgG
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anti-Wolfram Syndrome 1 (WFS1) (AA 61-313) antibody
WFS1 适用: 人, 猴 WB, IHC, ICC, ELISA, FACS, IF 宿主: 兔 Polyclonal unconjugated
anti-Wolfram Syndrome 1 (WFS1) (AA 1-285) antibodyWFS1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Wolfram Syndrome 1 (WFS1) (Internal Region) antibodyWFS1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Wolfram Syndrome 1 (WFS1) (AA 791-890) antibodyWFS1 适用: 人 WB, ICC, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- WFS1 (Wolfram Syndrome 1 (WFS1))
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别名
- WFS1
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背景
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Background: Wolframin is a protein that in humans is encoded by the WFS1 gene. This gene encodes a transmembrane protein, which is located primarily in the endoplasmic reticulum and ubiquitously expressed with highest levels in brain, pancreas, heart, and insulinoma beta-cell lines. Mutations in this gene are associated with Wolfram syndrome, also called DIDMOAD (Diabetes Insipidus, Diabetes Mellitus, Optic Atrophy, and Deafness), an autosomal recessive disorder. The disease affects the brain and central nervous system. Mutations in this gene can also cause autosomal dominant deafness 6 (DFNA6), also known as DFNA14 or DFNA38. Alternatively spliced transcript variants have been found for this gene.
Gene Full Name: wolframin ER transmembrane glycoprotein
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基因ID
- 7466
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UniProt
- O76024
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途径
- Sensory Perception of Sound, Carbohydrate Homeostasis, ER-Nucleus Signaling, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome
抗原
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