PROC 抗体 (C-Term)
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Quick Overview for PROC 抗体 (C-Term) (ABIN8053774)
抗原
See all PROC 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- C-Term
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原理
- Anti-Protein C/PROC Antibody
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Protein C/PROC Antibody. Tested in Flow Cytometry, IHC, ICC, WB applications. This antibody reacts with Human.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human Protein C.
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亚型
- IgG
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anti-Vitamin K-dependent protein C (PROC) (AA 32-131) antibody
PROC 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 3A10 unconjugated
anti-Vitamin K-dependent protein C (PROC) antibodyPROC 适用: 人 IHC, ELISA, IHC (p), IEP 宿主: 山羊 Polyclonal unconjugated
anti-Vitamin K-dependent protein C (PROC) (C-Term) antibodyPROC 适用: 人 WB, IHC, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Vitamin K-dependent protein C (PROC) (AA 177-206) antibodyPROC 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB33669 unconjugated
anti-Vitamin K-dependent protein C (PROC) (AA 1-236) antibodyPROC 适用: 人 WB, IHC, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Vitamin K-dependent protein C (PROC) antibodyPROC 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Vitamin K-dependent protein C (PROC) (AA 197-436) antibodyPROC 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Vitamin K-dependent protein C (PROC) (AA 17-166) antibodyPROC 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Vitamin K-dependent protein C (PROC) (AA 1-166) antibodyPROC 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E6 unconjugated
anti-Vitamin K-dependent protein C (PROC) antibodyPROC 适用: 人 IHC, ELISA, IHC (p), IEP 宿主: 绵羊 Polyclonal unconjugated
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应用备注
- Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, HumanWestern blot, 0.1-0.5 μg/mL, HumanImmunohistochemistry (Frozen Section), 0.5-1 μg/mL, Human Immunocytochemistry, 0.5-1 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Sodium azide, Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- PROC (Vitamin K-dependent protein C (PROC))
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别名
- PROC
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背景
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Background: Protein C (PROC), also called PC, is a zymogenic (inactive) protein, the activated form of which plays an important role in regulating blood clotting, inflammation, cell death and maintaining the permeability of blood vessel walls in humans and other animals. The PROC gene is mapped on 2q14.3. The PROC gene contains 8 exons and spans about 11 kb by Foster et al. The conversion of protein C to a protease with anticoagulant function by thrombin requires as a cofactor thrombomodulin, an endothelial cell membrane protein. Riewald et al. demonstrated that activated protein C uses the endothelial cell protein C receptor as a coreceptor for cleavage of protease-activated receptor-1 on endothelial cells. Faust et al. demonstrated that the endothelial pathways required for protein C activation are impaired in severe meningococcal sepsis. They stated that improvement in the outcome of children with meningococcal sepsis who were treated with unactivated protein C concentrates had been described in case reports and in 1 uncontrolled series.
Gene Full Name: protein C, inactivator of coagulation factors Va and VIIIa
Sequence Similarities: Belongs to the peptidase S1 family.
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分子量
- 36 kDa
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基因ID
- 5624
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UniProt
- P04070
抗原
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