Vitamin D Receptor 抗体 (C-Term) (Fluoro488)
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Quick Overview for Vitamin D Receptor 抗体 (C-Term) (Fluoro488) (ABIN8053733)
抗原
See all Vitamin D Receptor (VDR) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Anti-Vitamin D Receptor/VDR Antibody Fluoro488 Conjugated
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human Vitamin D Receptor/VDR, which shares 88.9% amino acid (aa) sequence identity with mouse and rat VDR.
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亚型
- IgG
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anti-Vitamin D Receptor (VDR) (AA 65-180) antibody
VDR 适用: 人, 小鼠, 大鼠 WB, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Vitamin D Receptor (VDR) (Internal Region) antibodyVDR 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Vitamin D Receptor (VDR) (AA 1-427) antibodyVDR 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Vitamin D Receptor (VDR) (AA 1-300) antibodyVDR 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Vitamin D Receptor (VDR) (C-Term) antibodyVDR 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Vitamin D Receptor (VDR) (pSer208) antibodyVDR 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Vitamin D Receptor (VDR) (N-Term) antibodyVDR 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Vitamin D Receptor (VDR) (AA 266-422) antibodyVDR 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Vitamin D Receptor (VDR) (AA 1-427) antibodyVDR 适用: 人 ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2F4 unconjugated
anti-Vitamin D Receptor (VDR) (AA 1-428) antibodyVDR 适用: 人 ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2F4 unconjugated
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- Vitamin D Receptor (VDR)
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别名
- VDR
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物质类
- Chemical
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背景
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Background: VDR (Vitamin D Receptor), also known as Vitamin D Hormone Receptor, is a member of the nuclear receptor family of transcription factors. Labuda et al. (1991) assigned the VDR gene to 12q12-q14 by in situ hybridization. Using mutation analysis, Jurutka et al. (2000) characterized arg18/arg22, VDR residues immediately N-terminal of the first DNA-binding zinc finger, as vital for contact with the general transcription factor IIB (TFIIB). A natural polymorphic variant of VDR, termed F/M4 (missing a FokI restriction site), which lacks only the first 3 amino acids (including glu2), interacted more efficiently with TFIIB and also possessed elevated transcriptional activity compared with the full-length (f/M1) receptor. Shah et al. (2006) stated that the signaling and oncogenic activity of beta-catenin (CTNNB1) can be repressed by activation of VDR. Conversely, high levels of beta-catenin can potentiate the transcriptional activity of 1,25- dihydroxyvitamin D3.
Gene Full Name: vitamin D receptor
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基因ID
- 7421
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UniProt
- P11473
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途径
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
抗原
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