Versican 抗体 (N-Term) (FITC)
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北京 101111
Quick Overview for Versican 抗体 (N-Term) (FITC) (ABIN8053604)
抗原
See all Versican (Vcan) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- Anti-Versican/VCAN Antibody FITC Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- different from the related mouse,rat sequences by two amino acids.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human Versican, different from the related mouse and rat sequences by two amino acids.
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亚型
- IgG
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anti-Versican (Vcan) (AA 3301-3396) antibody
Vcan 适用: 小鼠, 大鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Versican (Vcan) (AA 3058-3299) antibodyVcan 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Versican (Vcan) antibodyVcan 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Versican (Vcan) (AA 2958-3209) antibodyVcan 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Versican (Vcan) antibodyKD Validated Vcan 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB2380 unconjugated Recombinant Antibody
anti-Versican (Vcan) (AA 362-585) antibody (Atto 390)Vcan 适用: 小鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S351-23 Atto 390
anti-Versican (Vcan) (AA 362-585) antibody (Atto 488)Vcan 适用: 小鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S351-23 Atto 488
anti-Versican (Vcan) (AA 362-585) antibody (APC)Vcan 适用: 小鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S351-23 APC
anti-Versican (Vcan) (AA 362-585) antibody (Atto 594)Vcan 适用: 小鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S351-23 Atto 594
anti-Versican (Vcan) (AA 362-585) antibody (Biotin)Vcan 适用: 小鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S351-23 Biotin
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- Versican (Vcan)
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别名
- VCAN
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背景
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Background: Versican (VCAN), also known as CSPG2, is a large extracellular matrix proteoglycan that is present in a variety of human tissues. Versican is a large chondroitin sulfate proteoglycan with an apparent molecular mass of more than 1000 kDa. The Versican gene is mapped on 5q14.2-q14.3. The human versican gene contains 15 exons spanning more than 90 kb. The distribution of versican by using affinity-purified polyclonal antibodies that recognize the core protein of the prominent versican splice variants V0 and V1. Versican staining was noted in the central and peripheral nervous system, in the basal layer of the epidermis, and on the luminal surface of some glandular epithelia. Biochemical purification of LLC-conditioned medium led to identification of the extracellular matrix proteoglycan versican, which is upregulated in many human tumors including lung cancer, as a macrophage activator that acts through TLR2 and its coreceptors TLR6 and CD14. By activating TLR2:TLR6 complexes and inducing TNF-alpha secretion by myeloid cells, versican strongly enhances LLC metastatic growth.
Gene Full Name: versican
Sequence Similarities: Belongs to the aggrecan/versican proteoglycan family.
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基因ID
- 1462
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UniProt
- P13611
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途径
- Glycosaminoglycan Metabolic Process
抗原
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