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VCAM1 抗体 (AA 25-739) (HRP)

This 兔 多克隆 antibody specifically detects VCAM1 in WB, IHC 和 ELISA. It exhibits reactivity toward 人.
产品编号 ABIN8053385
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for VCAM1 抗体 (AA 25-739) (HRP) (ABIN8053385)

抗原

See all VCAM1 抗体
VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))

适用

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宿主

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克隆类型

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多克隆

标记

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This VCAM1 antibody is conjugated to HRP

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

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    AA 25-739

    原理

    Anti-VCAM1 Antibody HRP Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human VCAM1 recombinant protein (Position: F25-V739).

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))

    别名

    VCAM1

    背景

    Background: CD106(cluster of differentiation 106) also known as vascular cell adhesion molecule 1(VCAM-1), is a protein that in humans is encoded by the VCAM1 gene. In inflammatory conditions and in cardiac allografts undergoing rejection, VCAM1 is upregulated in endothelium of postcapillary venules. Arterial expression of VCAM1 is also found in experimental models of atherosclerosis in the rabbit. This gene is mapped to chromosome 1 by Southern analysis of somatic cell hybrids. VCAM-1 functions as a cell adhesion molecule. The VCAM-1 protein mediates the adhesion of lymphocytes, monocytes, eosinophils, andbasophils to vascularendothelium. It also functions in leukocyte-endothelial cell signal transduction, and it may play a role in the development ofatherosclerosis and rheumatoid arthritis. CAM741 works similar to cotransin in that it represses the biosynthesis of VCAM1 cells by blocking the process of cotranslational translocation, which is dependent on the signal peptide ofVCAM1. Among the lung metastasis signature genes identified, several, includingVCAM1, were functionally validated.

    Gene Full Name: vascular cell adhesion molecule 1

    基因ID

    7412

    UniProt

    P19320

    途径

    Carbohydrate Homeostasis
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