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VNN1 抗体 (AA 22-192) (PE)

This 兔 多克隆 antibody specifically detects VNN1 in FACS. It exhibits reactivity toward 人.
产品编号 ABIN8053343
发货至: 中国
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Quick Overview for VNN1 抗体 (AA 22-192) (PE) (ABIN8053343)

抗原

See all VNN1 抗体
VNN1 (Vanin 1 (VNN1))

适用

  • 71
  • 23
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  • 1

宿主

  • 66
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克隆类型

  • 68
  • 11
多克隆

标记

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This VNN1 antibody is conjugated to PE

应用范围

  • 57
  • 24
  • 21
  • 17
  • 15
  • 15
  • 13
  • 13
  • 4
  • 4
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Flow Cytometry (FACS)
  • 抗原表位

    • 16
    • 11
    • 5
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    • 1
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    AA 22-192

    原理

    Anti-VNN1 Antibody PE Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    预测反应

    coli-derived human VNN1 recombinant protein (Position: Q22-K192). Human VNN1 shares 82.2% amino acid (aa) sequence identity with mouse VNN1.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E. coli-derived human VNN1 recombinant protein (Position: Q22-K192). Human VNN1 shares 82.2% amino acid (aa) sequence identity with mouse VNN1.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    VNN1 (Vanin 1 (VNN1))

    别名

    VNN1

    背景

    Background: Pantetheinase is an enzyme that in humans is encoded by the VNN1 gene. This gene encodes a member of the vanin family of proteins, which share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. This protein, like its mouse homolog, is likely a GPI-anchored cell surface molecule. The mouse protein is expressed by the perivascular thymic stromal cells and regulates migration of T-cell progenitors to the thymus. This gene lies in close proximity to, and in the same transcriptional orientation as, two other vanin genes on chromosome 6q23-q24.

    Gene Full Name: vanin 1

    基因ID

    8876

    UniProt

    O95497

    途径

    Negative Regulation of intrinsic apoptotic Signaling
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