CrkL 抗体 (AA 1-290)
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北京 101111
Quick Overview for CrkL 抗体 (AA 1-290) (ABIN8053004)
抗原
See all CrkL (CRKL) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 1-290
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原理
- Anti-CRKL Antibody
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交叉反应 (详细)
- No cross-reactivity with other proteins
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产品特性
- Anti-CRKL Antibody. Tested in ELISA, Flow Cytometry, IP, IF, ICC, WB applications. This antibody reacts with Human.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human CRKL recombinant protein (Position: M1-H290).
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亚型
- IgG
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应用备注
- Western blot, 0.25-0.5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Immunoprecipitation, 0.5-2 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
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- CrkL (CRKL) (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL))
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别名
- CRKL
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背景
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Background: Crk-like protein is a protein that in humans is encoded by the CRKL gene. This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.
Gene Full Name: CRK like proto-oncogene, adaptor protein
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分子量
- 34 kDa
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基因ID
- 1399
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UniProt
- P46109
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途径
- Interferon-gamma Pathway, Neurotrophin Signaling Pathway, Signaling of Hepatocyte Growth Factor Receptor
抗原
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