CrkL 抗体 (AA 1-290) (HRP)
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Quick Overview for CrkL 抗体 (AA 1-290) (HRP) (ABIN8053000)
抗原
See all CrkL (CRKL) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-290
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原理
- Anti-CRKL Antibody HRP Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human CRKL recombinant protein (Position: M1-H290).
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亚型
- IgG
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- CrkL (CRKL) (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL))
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别名
- CRKL
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背景
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Background: Crk-like protein is a protein that in humans is encoded by the CRKL gene. This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.
Gene Full Name: CRK like proto-oncogene, adaptor protein
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基因ID
- 1399
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UniProt
- P46109
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途径
- Interferon-gamma Pathway, Neurotrophin Signaling Pathway, Signaling of Hepatocyte Growth Factor Receptor
抗原
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