Utrophin 抗体 (AA 1211-2294) (APC)
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Quick Overview for Utrophin 抗体 (AA 1211-2294) (APC) (ABIN8052946)
抗原
See all Utrophin (UTRN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1211-2294
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原理
- Anti-Utrophin/UTRN Antibody APC Conjugated
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Utrophin/UTRN recombinant protein (Position: L1211-K2294).
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亚型
- IgG
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anti-Utrophin (UTRN) (AA 1-252) antibody
UTRN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Utrophin (UTRN) (AA 3328-3433) antibodyUTRN 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 5G6 unconjugated
anti-Utrophin (UTRN) antibodyUTRN 适用: 人 IHC 宿主: 小鼠 Monoclonal DRP3-20C5 unconjugated
anti-Utrophin (UTRN) (AA 3328-3433) antibodyUTRN 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- Utrophin (UTRN)
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别名
- UTRN
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背景
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Background: Utrophin is a protein that in humans is encoded by the UTRN gene. This gene shares both structural and functional similarities with the dystrophin gene. It contains an actin-binding N-terminus, a triple coiled-coil repeat central region, and a C-terminus that consists of protein-protein interaction motifs which interact with dystroglycan protein components. The protein encoded by this gene is located at the neuromuscular synapse and myotendinous junctions, where it participates in post-synaptic membrane maintenance and acetylcholine receptor clustering. Mouse studies suggest that this gene may serve as a functional substitute for the dystrophin gene and therefore, may serve as a potential therapeutic alternative to muscular dystrophy which is caused by mutations in the dystrophin gene. Alternative splicing of the utrophin gene has been described, however, the full-length nature of these variants has not yet been determined.
Gene Full Name: utrophin
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基因ID
- 7402
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UniProt
- P46939
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途径
- Skeletal Muscle Fiber Development
抗原
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