UBA1 抗体 (N-Term)
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Quick Overview for UBA1 抗体 (N-Term) (ABIN8052474)
抗原
See all UBA1 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- N-Term
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原理
- Anti-E1 Ubiquitin Activating Enzyme/UBA1 Antibody
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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预测反应
- different from the related mouse,rat sequences by one amino acid.
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产品特性
- Anti-E1 Ubiquitin Activating Enzyme/UBA1 Antibody. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human UBA1, different from the related mouse and rat sequences by one amino acid.
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亚型
- IgG
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anti-Ubiquitin-Like Modifier Activating Enzyme 1 (UBA1) (AA 300-600) antibody
UBA1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Like Modifier Activating Enzyme 1 (UBA1) antibodyUBA1 适用: 人, 大鼠, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Like Modifier Activating Enzyme 1 (UBA1) (AA 1-1058) antibodyUBA1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2B6 unconjugated
anti-Ubiquitin-Like Modifier Activating Enzyme 1 (UBA1) (AA 730-881) antibodyUBA1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Like Modifier Activating Enzyme 1 (UBA1) antibodyUBA1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Like Modifier Activating Enzyme 1 (UBA1) (AA 1008-1058) antibodyUBA1 适用: 人, 小鼠 WB, IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Like Modifier Activating Enzyme 1 (UBA1) antibodyKD Validated UBA1 适用: 人 WB 宿主: 兔 Monoclonal 25GB7860 unconjugated Recombinant Antibody
anti-Ubiquitin-Like Modifier Activating Enzyme 1 (UBA1) (AA 961-1058) antibodyUBA1 适用: 人, 大鼠 ELISA, IF (cc), IHC (p), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Like Modifier Activating Enzyme 1 (UBA1) (AA 800-850) antibodyUBA1 适用: 人 IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Like Modifier Activating Enzyme 1 (UBA1) (N-Term) antibodyUBA1 适用: 人, 大鼠, 小鼠, 犬, Cow, 马, 兔, 豚鼠, Bat, Hamster, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- UBA1 (Ubiquitin-Like Modifier Activating Enzyme 1 (UBA1))
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别名
- UBA1
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背景
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Background: Ubiquitin-like modifier activating enzyme 1 (UBA1) is an enzyme which in humans is encoded by the UBA1 gene. The protein encoded by this gene catalyzes the first step in ubiquitin conjugation, or ubiquitination, to mark cellular proteins for degradation. Specifically, UBA1 catalyzes the ATP-dependent adenylation of ubiquitin (Ub), thereby forming a thioester bond between the two. It also continues to participate in subsequent steps of ubiquination as a Ub carrier. UBA1 is one of only two human ubiquitin-activating enzymes (E1), the other being UBA6, and thus is largely responsible for protein ubiquitination in humans. Through its central role in ubiquitination, UBA1 has been linked to cell cycle regulation, endocytosis, signal transduction, apoptosis, DNA damage repair, and transcriptional regulation. Additionally, UBE1 helps regulate the NEDD8 pathway, thus implicating it in protein folding, as well as mitigating the depletion of ubiquitin levels during stress.
Gene Full Name: ubiquitin like modifier activating enzyme 1
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分子量
- 117 kDa
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基因ID
- 7317
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UniProt
- P22314
抗原
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