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Tumor Protein p73 抗体 (AA 1-198)

The 兔 多克隆 anti-Tumor Protein p73 antibody is suitable to detect Tumor Protein p73 in samples from 人, 小鼠 和 大鼠. It has been validated for WB 和 IHC.
产品编号 ABIN8051676
发货至: 中国
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Quick Overview for Tumor Protein p73 抗体 (AA 1-198) (ABIN8051676)

抗原

See all Tumor Protein p73 (TP73) 抗体
Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))

适用

  • 161
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人, 小鼠, 大鼠

宿主

  • 139
  • 23

克隆类型

  • 118
  • 44
多克隆

标记

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This Tumor Protein p73 antibody is un-conjugated

应用范围

  • 97
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Western Blotting (WB), Immunohistochemistry (IHC)

质量等级

Carrier-free
  • 抗原表位

    • 25
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    • 1
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    AA 1-198

    原理

    Anti-p73/TP73 Antibody

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Human p73 shares 96% amino acid (aa) sequence identity with mouse p73.

    产品特性

    Anti-p73/TP73 Antibody. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human p73 recombinant protein (Position: M1-E198). Human p73 shares 96% amino acid (aa) sequence identity with mouse p73.

    亚型

    IgG
  • 应用备注

    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, RatWestern blot, 0.1-0.5 μg/mL, Human

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))

    别名

    TP73

    背景

    Background: p73, also known as tumor protein 73 (TP73), encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It is mapped to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Furthermore, recent finding are suggesting that over-expression of transcription factors involved in cell cycle regulation and synthesis of DNA in mammalian cells (e.g.: E2F-1) induces the expression of p73. In addition, p73 is a substrate of the c-Abl kinase and that the ability of c-Abl to phosphorylate p73 is markedly increased by gamma-irradiation.

    Gene Full Name: tumor protein p73

    Sequence Similarities: Belongs to the p53 family.

    分子量

    73 kDa

    基因ID

    7161

    UniProt

    O15350

    途径

    Regulation of Cell Size, Positive Regulation of Response to DNA Damage Stimulus
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