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Tumor Protein p73 抗体 (AA 1-198) (PE)

The PE-conjugated 兔 多克隆 anti-Tumor Protein p73 antibody (ABIN8051674) specifically detects Tumor Protein p73 in FACS. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN8051674
发货至: 中国
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Quick Overview for Tumor Protein p73 抗体 (AA 1-198) (PE) (ABIN8051674)

抗原

See all Tumor Protein p73 (TP73) 抗体
Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))

适用

  • 161
  • 73
  • 54
  • 5
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  • 1
人, 小鼠, 大鼠

宿主

  • 139
  • 23

克隆类型

  • 118
  • 44
多克隆

标记

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  • 1
  • 1
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This Tumor Protein p73 antibody is conjugated to PE

应用范围

  • 98
  • 62
  • 39
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  • 15
  • 13
  • 12
  • 10
  • 6
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Flow Cytometry (FACS)
  • 抗原表位

    • 25
    • 15
    • 12
    • 9
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    • 3
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    • 2
    • 2
    • 2
    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    AA 1-198

    原理

    Anti-p73/TP73 Antibody PE Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Human p73 shares 96% amino acid (aa) sequence identity with mouse p73.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human p73 recombinant protein (Position: M1-E198). Human p73 shares 96% amino acid (aa) sequence identity with mouse p73.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))

    别名

    TP73

    背景

    Background: p73, also known as tumor protein 73 (TP73), encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It is mapped to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Furthermore, recent finding are suggesting that over-expression of transcription factors involved in cell cycle regulation and synthesis of DNA in mammalian cells (e.g.: E2F-1) induces the expression of p73. In addition, p73 is a substrate of the c-Abl kinase and that the ability of c-Abl to phosphorylate p73 is markedly increased by gamma-irradiation.

    Gene Full Name: tumor protein p73

    Sequence Similarities: Belongs to the p53 family.

    基因ID

    7161

    UniProt

    O15350

    途径

    Regulation of Cell Size, Positive Regulation of Response to DNA Damage Stimulus
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