CREM 抗体 (AA 251-361) (Biotin)
Quick Overview for CREM 抗体 (AA 251-361) (Biotin) (ABIN755364)
抗原
See all CREM 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 251-361
-
交叉反应
- 人, 小鼠
-
预测反应
- Rat,Pig,Horse,Chicken
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from human CREM
-
亚型
- IgG
-
-
-
-
应用备注
-
IHC-P 1:200-400
IHC-F 1:100-500 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C for 12 months.
-
有效期
- 12 months
-
-
- CREM (CAMP Responsive Element Modulator (CREM))
-
别名
- CREM
-
背景
-
Synonyms: cAMP response element modulator, CREM-1, cAMP responsive element modulator, hCREM 2, hCREM2, ICER, Inducible cAMP early repressor, Inducible cAMP early repressor ICER, MGC111110, MGC17881, MGC41893.
Background: CREM is a a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is derived from a multiexonic gene that encodes both activators and antagonists of cAMP-inducible transcription by differential splicing. Splice variants with antagonistic function lack 2 glutamine-rich domains and block cAMP-induced transcription, whereas an isoform that includes these glutamine-rich domains is a transcriptional activator.
-
基因ID
- 1390
-
UniProt
- Q03060
-
途径
- Retinoic Acid Receptor Signaling Pathway
抗原
-