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STING/TMEM173 抗体 (C-Term)

The 兔 多克隆 anti-STING/TMEM173 antibody is suitable to detect STING/TMEM173 in samples from 人 和 小鼠. It has been validated for WB, IHC 和 FACS.
产品编号 ABIN8049063
发货至: 中国
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Quick Overview for STING/TMEM173 抗体 (C-Term) (ABIN8049063)

抗原

See all STING/TMEM173 (TMEM173) 抗体
STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))

适用

  • 111
  • 33
  • 33
  • 2
  • 1
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  • 1
人, 小鼠

宿主

  • 122
  • 10

克隆类型

  • 82
  • 50
多克隆

标记

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  • 9
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  • 1
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  • 1
  • 1
  • 1
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This STING/TMEM173 antibody is un-conjugated

应用范围

  • 82
  • 38
  • 34
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  • 20
  • 20
  • 18
  • 13
  • 13
  • 12
  • 3
  • 3
  • 1
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Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

质量等级

Carrier-free
  • 抗原表位

    • 29
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    • 10
    • 8
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    • 1
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    • 1
    C-Term

    原理

    Anti-TMEM173 Antibody

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    different from the related mouse sequence by five amino acids.

    产品特性

    Anti-TMEM173 Antibody. Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human TMEM173, different from the related mouse sequence by five amino acids.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human, Mouse Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human Flow Cytometry(Fixed), 1-3 μg/1x106 cells, Human

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))

    别名

    TMEM173

    背景

    Background: Transmembrane protein 173 is a protein that in humans is encoded by the TMEM173 gene. This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. Also the encoded protein has been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.

    Gene Full Name: stimulator of interferon response cGAMP interactor 1

    Sequence Similarities: Belongs to the transcription factor STAT family.

    分子量

    35 kDa

    基因ID

    340061

    UniProt

    Q86WV6

    途径

    Activation of Innate immune Response
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