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STING/TMEM173 抗体 (C-Term) (Cy3)

The 兔 多克隆 anti-STING/TMEM173 antibody is suitable to detect STING/TMEM173 in samples from 人 和 小鼠. It has been validated for FACS.
产品编号 ABIN8049054
发货至: 中国
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Quick Overview for STING/TMEM173 抗体 (C-Term) (Cy3) (ABIN8049054)

抗原

See all STING/TMEM173 (TMEM173) 抗体
STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))

适用

  • 111
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人, 小鼠

宿主

  • 122
  • 10

克隆类型

  • 82
  • 50
多克隆

标记

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This STING/TMEM173 antibody is conjugated to Cy3

应用范围

  • 83
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Flow Cytometry (FACS)
  • 抗原表位

    • 29
    • 15
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    • 5
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    • 1
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    C-Term

    原理

    Anti-TMEM173 Antibody Cy3 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    different from the related mouse sequence by five amino acids.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human TMEM173, different from the related mouse sequence by five amino acids.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, 1-3 μg/1x106 cells

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))

    别名

    TMEM173

    背景

    Background: Transmembrane protein 173 is a protein that in humans is encoded by the TMEM173 gene. This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. Also the encoded protein has been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.

    Gene Full Name: stimulator of interferon response cGAMP interactor 1

    Sequence Similarities: Belongs to the transcription factor STAT family.

    基因ID

    340061

    UniProt

    Q86WV6

    途径

    Activation of Innate immune Response
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