TIGAR 抗体 (AA 1-270) (HRP)
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北京 101111
Quick Overview for TIGAR 抗体 (AA 1-270) (HRP) (ABIN8047628)
抗原
See all TIGAR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-270
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原理
- Anti-TIGAR Antibody HRP Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins
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预测反应
- Human TIGAR shares 72.8% amino acid (aa) sequence identity with mouse TIGAR.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human TIGAR recombinant protein (Position: M1-R270). Human TIGAR shares 72.8% amino acid (aa) sequence identity with mouse TIGAR.
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亚型
- IgG
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- TIGAR (TP53 induced glycolysis regulatory phosphatase (TIGAR))
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别名
- TIGAR
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背景
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Background: This gene is regulated as part of the p53 tumor suppressor pathway and encodes a protein with sequence similarity to the bisphosphate domain of the glycolytic enzyme that degrades fructose-2,6-bisphosphate. The protein functions by blocking glycolysis and directing the pathway into the pentose phosphate shunt. Expression of this protein also protects cells from DNA damaging reactive oxygen species and provides some protection from DNA damage-induced apoptosis. The 12p13.32 region that includes this gene is paralogous to the 11q13.3 region.
Gene Full Name: TP53 induced glycolysis regulatory phosphatase
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基因ID
- 57103
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UniProt
- Q9NQ88
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途径
- Warburg Effect
抗原
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