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TJP1 抗体 (AA 1178-1527) (Fluoro488)

The 小鼠 单克隆 anti-TJP1 antibody is suitable to detect TJP1 in samples from 人. It has been validated for FACS.
产品编号 ABIN8046744
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for TJP1 抗体 (AA 1178-1527) (Fluoro488) (ABIN8046744)

抗原

See all TJP1 抗体
TJP1 (Tight Junction Protein 1 (TJP1))

适用

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宿主

  • 69
  • 14
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小鼠

克隆类型

  • 71
  • 18
单克隆

标记

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This TJP1 antibody is conjugated to Fluoro488

应用范围

  • 63
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Flow Cytometry (FACS)

克隆位点

3E12
  • 抗原表位

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    AA 1178-1527

    原理

    Anti-TJP1 Antibody (monoclonal, 3E12) Fluoro488 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    预测反应

    Human TJP1 shares 82% amino acid (aa) sequence identity with mouse TJP1.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human TJP1 recombinant protein (Position: H1178-F1527). Human TJP1 shares 82% amino acid (aa) sequence identity with mouse TJP1.

    亚型

    IgG1
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    TJP1 (Tight Junction Protein 1 (TJP1))

    别名

    TJP1

    背景

    Background: Gamma-interferon-inducible protein Ifi-16 (Ifi-16) also known as interferon-inducible myeloid differentiation transcriptional activator is a protein that in humans is encoded by the IFI16 gene. This gene encodes a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein-protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma-1. It modulates p53 function, and inhibits cell growth in the Ras/Raf signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

    Gene Full Name: tight junction protein 1

    UniProt

    Q07157

    途径

    Carbohydrate Homeostasis, Cell-Cell Junction Organization
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