TJP1 抗体 (AA 1178-1527) (Cy3)
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Quick Overview for TJP1 抗体 (AA 1178-1527) (Cy3) (ABIN8046743)
抗原
See all TJP1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1178-1527
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原理
- Anti-TJP1 Antibody (monoclonal, 3E12) Cy3 Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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预测反应
- Human TJP1 shares 82% amino acid (aa) sequence identity with mouse TJP1.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human TJP1 recombinant protein (Position: H1178-F1527). Human TJP1 shares 82% amino acid (aa) sequence identity with mouse TJP1.
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亚型
- IgG1
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应用备注
- Flow Cytometry, 1-3 μg/1x106 cells
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- TJP1 (Tight Junction Protein 1 (TJP1))
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别名
- TJP1
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背景
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Background: Gamma-interferon-inducible protein Ifi-16 (Ifi-16) also known as interferon-inducible myeloid differentiation transcriptional activator is a protein that in humans is encoded by the IFI16 gene. This gene encodes a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein-protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma-1. It modulates p53 function, and inhibits cell growth in the Ras/Raf signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene Full Name: tight junction protein 1
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UniProt
- Q07157
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途径
- Carbohydrate Homeostasis, Cell-Cell Junction Organization
抗原
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