TJP1 抗体 (AA 1178-1527) (Fluoro647)
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北京 101111
Quick Overview for TJP1 抗体 (AA 1178-1527) (Fluoro647) (ABIN8046740)
抗原
See all TJP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1178-1527
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原理
- Anti-ZO1 tight junction protein/TJP1 Antibody Fluoro647 Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins
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预测反应
- Human TJP1 shares 82% amino acid (aa) sequence identity with mouse TJP1.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human TJP1 recombinant protein (Position: H1178-F1527). Human TJP1 shares 82% amino acid (aa) sequence identity with mouse TJP1.
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- TJP1 (Tight Junction Protein 1 (TJP1))
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别名
- TJP1
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背景
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Background: Tight junction protein ZO-1 is a protein that in humans is encoded by the TJP1 gene. It is mapped to 15q13.1. This gene encodes a protein located on a cytoplasmic membrane surface of intercellular tight junctions. The encoded protein may be involved in signal transduction at cell-cell junctions. It has been found that injected CagA associates with the epithelial tight-junction scaffolding protein TJP1 and the transmembrane protein junctional adhesion molecule, causing an ectopic assembly of tight junction components at sites of bacterial attachment, and altering the composition and function of the apical-junctional complex.
Gene Full Name: tight junction protein 1
Sequence Similarities: Belongs to the MAGUK family.
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基因ID
- 7082
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UniProt
- Q07157
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途径
- Carbohydrate Homeostasis, Cell-Cell Junction Organization
抗原
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