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TYMS 抗体 (AA 1-313) (Fluoro647)

The 兔 多克隆 anti-TYMS antibody is suitable to detect TYMS in samples from 人, 大鼠 和 猴. It has been validated for FACS.
产品编号 ABIN8046531
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for TYMS 抗体 (AA 1-313) (Fluoro647) (ABIN8046531)

抗原

See all TYMS 抗体
TYMS (Thymidylate Synthetase (TYMS))

适用

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人, 大鼠, 猴

宿主

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  • 71
  • 1

克隆类型

  • 98
  • 57
多克隆

标记

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This TYMS antibody is conjugated to Fluoro647

应用范围

  • 81
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Flow Cytometry (FACS)
  • 抗原表位

    • 31
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    • 1
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    AA 1-313

    原理

    Anti-Thymidylate Synthase/TYMS Antibody Fluoro647 Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human Thymidylate Synthase/TYMS recombinant protein (Position: M1-V313).

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    TYMS (Thymidylate Synthetase (TYMS))

    别名

    TYMS

    背景

    Background: Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using, 10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs. Expression of this gene and that of a naturally occurring antisense transcript, mitochondrial enolase superfamily member 1 (GeneID:55556), vary inversely when cell-growth progresses from late-log to plateau phase. Polymorphisms in this gene may be associated with etiology of neoplasia, including breast cancer, and response to chemotherapy.

    Gene Full Name: thymidylate synthetase

    基因ID

    7298

    UniProt

    P04818

    途径

    Mitotic G1-G1/S Phases
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