Thrombopoietin 抗体 (AA 22-259) (Cy3)
Our Local Distributor
北京 101111
Quick Overview for Thrombopoietin 抗体 (AA 22-259) (Cy3) (ABIN8046347)
抗原
See all Thrombopoietin (THPO) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 22-259
-
原理
- Anti-Thrombopoietin/Thpo Antibody Cy3 Conjugated
-
特异性
- No cross reactivity with other proteins.
-
交叉反应 (详细)
- No cross-reactivity with other proteins
-
预测反应
- coli-derived mouse Thrombopoietin recombinant protein (Position: S22-H259). Mouse Thrombopoietin shares 79.3%,92.9% amino acid (aa) sequence identity with human,rat Thrombopoietin,respectively.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E. coli-derived mouse Thrombopoietin recombinant protein (Position: S22-H259). Mouse Thrombopoietin shares 79.3% and 92.9% amino acid (aa) sequence identity with human and rat Thrombopoietin, respectively.
-
亚型
- IgG
-
-
-
-
应用备注
- Flow Cytometry, 1-3 μg/1x106 cells
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
-
有效期
- 12 months
-
-
- Thrombopoietin (THPO)
-
别名
- Thpo
-
背景
-
Background: Thrombopoietin (THPO), also known as megakaryocyte growth and development factor (MGDF), is a protein that in humans is encoded by the THPO gene. Megakaryocytopoiesis is the cellular development process that leads to platelet production. The main functional protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Mutations in this gene are the cause of thrombocythemia 1. Alternative promoter usage and differential splicing result in multiple transcript variants differing in the 5' UTR and/or coding region. Multiple AUG codons upstream of the main open reading frame (ORF) have been identified, and these upstream AUGs inhibit translation of the main ORF at different extent.
Gene Full Name: thrombopoietin
-
基因ID
- 21832
-
UniProt
- P40226
-
途径
- JAK/STAT Signaling, Hormone Activity
抗原
-