TXNIP 抗体 (AA 122-152)
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北京 101111
Quick Overview for TXNIP 抗体 (AA 122-152) (ABIN8046246)
抗原
See all TXNIP 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 122-152
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原理
- Anti-TXNIP Antibody
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交叉反应 (详细)
- No cross reactivity with other proteins.
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预测反应
- Human TXNIP shares 93.5% amino acid (aa) sequence identity with both mouse,rat TXNIP.
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产品特性
- Anti-TXNIP Antibody. Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human TXNIP recombinant protein (Position: D122-N152). Human TXNIP shares 93.5% amino acid (aa) sequence identity with both mouse and rat TXNIP.
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亚型
- IgG
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应用备注
- Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
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- TXNIP (Thioredoxin Interacting Protein (TXNIP))
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别名
- TXNIP
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背景
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Background: Thioredoxin-interacting protein is a protein that in humans is encoded by the TXNIP gene. This gene encodes a thioredoxin-binding protein that is a member of the alpha arrestin protein family. Thioredoxin is a thiol-oxidoreductase that is a major regulator of cellular redox signaling which protects cells from oxidative stress. This protein inhibits the antioxidative function of thioredoxin resulting in the accumulation of reactive oxygen species and cellular stress. This protein also functions as a regulator of cellular metabolism and of endoplasmic reticulum (ER) stress. This protein may also function as a tumor suppressor. Alternate splicing results in multiple transcript variants.
Gene Full Name: thioredoxin interacting protein
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分子量
- 50-55 kDa
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基因ID
- 10628
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UniProt
- Q9H3M7
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途径
- Protein targeting to Nucleus, Platelet-derived growth Factor Receptor Signaling, Inflammasome
抗原
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