TXNIP 抗体 (AA 5-391) (Fluoro594)
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北京 101111
Quick Overview for TXNIP 抗体 (AA 5-391) (Fluoro594) (ABIN8046229)
抗原
See all TXNIP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 5-391
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原理
- Anti-TXNIP Antibody Fluoro594 Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human TXNIP recombinant protein (Position: K5-Q391).
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- TXNIP (Thioredoxin Interacting Protein (TXNIP))
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别名
- TXNIP
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背景
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Background: Thioredoxin-interacting protein is a protein that in humans is encoded by the TXNIP gene. It is mapped to 1q21.1. This gene encodes a thioredoxin-binding protein that is a member of the alpha arrestin protein family. Thioredoxin is a thiol-oxidoreductase that is a major regulator of cellular redox signaling which protects cells from oxidative stress. This protein inhibits the antioxidative function of thioredoxin resulting in the accumulation of reactive oxygen species and cellular stress. This protein also functions as a regulator of cellular metabolism and of endoplasmic reticulum (ER) stress. This protein may also function as a tumor suppressor. Alternate splicing results in multiple transcript variants.
Gene Full Name: thioredoxin interacting protein
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基因ID
- 10628
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UniProt
- Q9H3M7
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途径
- Protein targeting to Nucleus, Platelet-derived growth Factor Receptor Signaling, Inflammasome
抗原
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