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SIRT6 抗体 (AA 121-220)

This anti-SIRT6 antibody is a 兔 多克隆 antibody detecting SIRT6 in WB, ELISA, IF (cc), IF (p) 和 IHC (fro). Suitable for 人.
产品编号 ABIN754918
发货至: 中国

Quick Overview for SIRT6 抗体 (AA 121-220) (ABIN754918)

抗原

See all SIRT6 抗体
SIRT6 (Sirtuin 6 (SIRT6))

适用

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宿主

  • 93
  • 14
  • 2

克隆类型

  • 87
  • 22
多克隆

标记

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This SIRT6 antibody is un-conjugated

应用范围

  • 89
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Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 15
    • 12
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 121-220

    交叉反应

    预测反应

    Mouse,Rat

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human SIRT6

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    SIRT6 (Sirtuin 6 (SIRT6))

    别名

    SIRT6

    背景

    Synonyms: 2810449N18Rik, AI043036, Mono ADP ribosyltransferase sirtuin 6, NAD-dependent deacetylase sirtuin-6, NAD-dependent protein deacetylase sirtuin-6, SIR2 like 6, SIR2 like protein 6, Sir2 related protein type 6, SIR2-like protein 6, SIR2L6, SIRT 6, SIRT6, SIR6_HUMAN, Sirtuin silent mating type information regulation 2 homolog 6 S. cerevisiae, Sirtuin 6, Sirtuin type 6, Sirtuin6.

    Background: NAD-dependent protein deacetylase. Has deacetylase activity towards 'Lys-9' and 'Lys-56' of histone H3. Modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. Deacetylates 'Lys-9' of histone H3 at NF-kappa-B target promoters and may down-regulate the expression of a subset of NF-kappa-B target genes. Deacetylation of nucleosomes interferes with RELA binding to target DNA. May be required for the association of WRN with telomeres during S-phase and for normal telomere maintenance. Required for genomic stability. Required for normal IGF1 serum levels and normal glucose homeostasis. Modulates cellular senescence and apoptosis. Regulates the production of TNF protein.

    基因ID

    51548
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