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TLN1 抗体 (Middle Region) (Biotin)

The Biotin-conjugated 兔 多克隆 anti-TLN1 antibody (ABIN8045299) specifically detects TLN1 in WB, ELISA 和 IHC. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN8045299
发货至: 中国
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Quick Overview for TLN1 抗体 (Middle Region) (Biotin) (ABIN8045299)

抗原

See all TLN1 抗体
TLN1 (Talin 1 (TLN1))

适用

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人, 小鼠, 大鼠

宿主

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  • 29
  • 1

克隆类型

  • 72
  • 29
多克隆

标记

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This TLN1 antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 26
    • 15
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    Middle Region

    原理

    Anti-Talin 1/TLN1 Antibody Biotin Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence in the middle region of human Talin 1, which shares 97.6% amino acid (aa) sequence identity with both mouse and rat Talin 1.

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    TLN1 (Talin 1 (TLN1))

    别名

    TLN1

    背景

    Background: Talin-1 is a protein that in humans is encoded by the TLN1 gene. This gene encodes a cytoskeletal protein that is concentrated in areas of cell-substratum and cell-cell contacts. The encoded protein plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It codistributes with integrins in the cell surface membrane in order to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells. The N-terminus of this protein contains elements for localization to cell-extracellular matrix junctions. The C-terminus contains binding sites for proteins such as beta-1-integrin, actin, and vinculin.

    Gene Full Name: talin 1

    基因ID

    7094

    UniProt

    Q9Y490

    途径

    Cell-Cell Junction Organization, ER-Nucleus Signaling, Maintenance of Protein Location
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